Public houses and civic tensions in early modern Bern

This article examines the delicate relationship between the civic privilege of wine retailing and the constitutional emphasis on order in a city republic. Burghers appreciated the revenues from beverage sales, while urban authorities worried about destabilizing effects. In the context of state formation, Bern claimed control over public houses throughout its territory, but closer analysis suggests that socio-economic and political interests were constantly renegotiated, not only within the capital but also between centre and periphery

Pottsian LFG

Potts (2005) provides an elegant and influential approach to the syntax and semantics of a wide range of 'parenthetical' constructions, including various kinds of supplementals/appositives and expressives, which have not received much attention in the LFG literature. The prospect of wholesale importation of Pottsian analyses for such constructions is appealing. However, there are (as Potts himself notes) problems with his approach from a resource sensitive perspective, such as is often assumed in LFG approaches to the syntax semantics interface. Potts sketches, but does not develop, a way of overcoming these problems. In this paper we attempt to develop his proposal and explore ways in which it can be implemented in the architecture of LFG. For exemplification, we focus on supplemental ('appositive', non-restrictive) relative clauses in English. A side effect of our discussion is thus a proposal for an LFG analysis of this construction, which appears to have been neglected hitherto

Mesorhizobium septentrionale sp nov and Mesorhizobium temperatum sp nov., isolated from Astragalus adsurgens growing in the northern regions of China

Ninety-five rhizobial strains isolated from Astragalus adsurgens growing in the northern regions of China were classified into three main groups, candidate species 1, 11 and 111, based on a polyphasic approach. Comparative analysis of full-length 16S rRNA gene sequences of representative strains showed that candidate species I and 11 were Mesorhizobium, while candidate species 111, which consisted of non-nodulating strains, was closely related to Agrobacterium tumefaciens. The phylogenetic relationships of the three candidate species and some related strains were also confirmed by the sequencing of glnA genes, which were used as an alternative chromosomal marker. The DNA-DNA relatedness was between 11.3 and 47-1 % among representative strains of candidate species I and 11 and the type strains of defined Mesorhizobium species. Candidate III had DNA relatedness of between 4(.)3 and 25(.)2 % with type strains of Agrobacterium tumefaciens and Agrobacterium rubi. Two novel species are proposed to accommodate candidate species I and 11, Mesorhizobium septentrionale sp. nov. (type strain, SIDW014(T) =CCBAU 11014(T) = HAMBI 2582(T)) and Mesorhizobium temperatum sp. nov. (type strain, SIDW018(T) = CCBAU 11018(T) =HAMBI 2583(T)), respectively. At least two distinct nodA sequences were identified among the strains. The numerically dominant nodA sequence type was most similar to that from the Mesorhizobium tianshanense type strain and was identified in strains belonging to the two novel species as well as other, as yet, undefined genome types. Host range studies indicate that the different nodA sequences correlate with different host ranges. Further comparative studies with the defined Agrobacterium species are needed to clarify the taxonomic identity of candidate species 111

Response to Corner Brook Pulp & Paper Tire Derived Fuel (TDF) Co-Firing Trial Project Proponent: Corner Brook Pulp & Paper Ltd. (Reg. 1539)

While acknowledging potential economic benefits for Corner Brook Pulp and Paper (CBPP) in using tire-derived fuel (TDF), we remain unconvinced of the net public and environmental health benefits of its use and are concerned with the methodology of the proposed test. We hope that this overview of our concerns can help the Department of Environment and Conservation (DEC) make an informed decision regarding the testing of TDF at CBPP. Guiding our submission is the precautionary principle, which has been adopted by all relevant parties, including the Government of Canada, the Government of Newfoundland and Labrador and CBPP. As such and in light of the issues below, it is our position that additional research is required before moving to a test trial. This can be achieved either by conducting a full Environmental Impact Statement, including component studies and additional public hearings, or by rejecting the undertaking outright

Structural characterization of the D290V mutation site in hnRNPA2 low-complexity-domain polymers.

Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2 to valine is believed to predispose patients to multisystem proteinopathy. Mutation of aspartic acid 262 of hnRNPA1 to either valine or asparagine has been linked to either amyotrophic lateral sclerosis or multisystem proteinopathy. Mutation of aspartic acid 378 of hnRNPDL to either asparagine or histidine has been associated with limb girdle muscular dystrophy. All three of these aspartic acid residues map to evolutionarily conserved regions of low-complexity (LC) sequence that may function in states of either intrinsic disorder or labile self-association. Here, we present a combination of solid-state NMR spectroscopy with segmental isotope labeling and electron microscopy on the LC domain of the hnRNPA2 protein. We show that, for both the wild-type protein and the aspartic acid 290-to-valine mutant, labile polymers are formed in which the LC domain associates into an in-register cross-β conformation. Aspartic acid 290 is shown to be charged at physiological pH and immobilized within the polymer core. Polymers of the aspartic acid 290-to-valine mutant are thermodynamically more stable than wild-type polymers. These observations give evidence that removal of destabilizing electrostatic interactions may be responsible for the increased propensity of the mutated LC domains to self-associate in disease-causing conformations

KOMPARASI STRUKTUR PERTUNJUKAN WAYANG KULIT JAWA DENGAN BALI DALAM LAKON ARJUNA WIWAHA

Abstract This research compares and contrasts the structure of Javanese Wayang Kulit (Shadow Puppet) Theatre and th performance of Balinese Shadow Theatre, enacting the same story derived from Arjuna Wiwaha poem. This research is primarily based on our experiences as both dalang practicioner and instructor, interviewing several Javanese and Balinese dalangs, and field research in Surakarta and Bali. Major part of this research analyzes the performance dramatic structure that includes the plot, setting, characterization, theme, and edification. In comparing yhe performance of both types of Wayang shadow theatre there are similarity, diversity, and overlapping structure of the two Wayang theatres

The National Minimum Wage and In-work Poverty

The analysis presented in this paper considers the impact on poverty rates of the Labour government�s tax and benefit policy changes in combination with the introduction of the National Minimum Wage (NMW). It examines the contribution of the NMW to direct poverty reduction and to �making work pay�. It concludes that the main contribution made by the NMW to poverty reduction at the household level is probably through its role in underpinning the operation of in-work top-up benefits

Temperature-dependent ion mixing and diffusion during sputtering of thin films of CrSi_2 on silicon

Measurements of sputtering yields and composition profiles have been carried out using backscattering spectrometry for samples of CrSi_2 on Si irradiated with 200‐keV Xe ions. When the CrSi_2 layer is thinner than the ion range, the sputtering yield ratio of Si to Cr increases from 3.5 for room‐temperature irradiation to 65 at 290 °C. For a thick sample, the corresponding increase is from 2.4 to 4.0. only. These changes are explained in terms of a rise in the Si surface concentration at 290 °C. The driving force for this process seems to be the establishment of stoichiometric CrSi_2 compound. Transport of Si to the surface is by ion mixing in the thin sample and thermal diffusion through the thick layer