41,886 research outputs found
Automatic differential analysis of NMR experiments in complex samples
Liquid state NMR is a powerful tool for the analysis of complex mixtures of
unknown molecules. This capacity has been used in many analytical approaches:
metabolomics, identification of active compounds in natural extracts,
characterization of species, and such studies require the acquisition of many
diverse NMR measurements on series of samples.
While acquisition can easily be performed automatically, the number of NMR
experiments involved in these studies increases very rapidly and this data
avalanche requires to resort to automatic processing and analysis.
We present here a program that allows the autonomous, unsupervised processing
of a large corpus of 1D, 2D and DOSY experiments from a series of samples
acquired in different conditions. The program provides all the signal
processing steps, as well as peak-picking and bucketing of 1D and 2D spectra,
the program and its components are fully available. In an experiment mimicking
the search of an active species in natural extract, we use it for the automatic
detection of small amounts of artemisin added to a series of plant extracts,
and for the generation of the spectral fingerprint of this molecules.
This program called Plasmodesma is a novel tool which should be useful to
decipher complex mixtures, particularly in the discovery of biologically active
natural products from plants extracts, but can also in drug discovery or
metabolomics studies.Comment: 35 pages, 36 figures, 26 reference
TurbuStat: Turbulence Statistics in Python
We present TurbuStat (v1.0): a Python package for computing turbulence
statistics in spectral-line data cubes. TurbuStat includes implementations of
fourteen methods for recovering turbulent properties from observational data.
Additional features of the software include: distance metrics for comparing two
data sets; a segmented linear model for fitting lines with a break-point; a
two-dimensional elliptical power-law model; multi-core fast-fourier-transform
support; a suite for producing simulated observations of fractional Brownian
Motion fields, including two-dimensional images and optically-thin HI data
cubes; and functions for creating realistic world coordinate system information
for synthetic observations. This paper summarizes the TurbuStat package and
provides representative examples using several different methods. TurbuStat is
an open-source package and we welcome community feedback and contributions.Comment: Accepted in AJ. 21 pages, 8 figure
Dataset for Sun dynamics from topological features
The present study presents an extensive dataset meticulously curated from solar images sourced from the Solar and Heliospheric Observatory (SOHO), encompassing a range of spectral bands. This collaborative effort spans multiple disciplines and culminates in a robust and automated methodology that traverses the entire spectrum from solar imaging to the computation of spectral parameters and relevant characteristics.
The significance of this undertaking lies in the profound insights yielded by the dataset. Encompassing diverse spectral bands and employing topological features, the dataset captures the multifaceted dynamics of solar activity, fostering interdisciplinary correlations and analyses with other solar phenomena. Consequently, the data's intrinsic value is greatly enhanced, affording researchers in solar physics, space climatology, and related fields the means to unravel intricate processes.
To achieve this, an open-source Python library script has been developed, consolidating three pivotal stages: image acquisition, image processing, and parameter calculation. Originally conceived as discrete modules, these steps have been unified into a single script, streamlining the entire process. Applying this script to various solar image types has generated multiple datasets, subsequently synthesized into a comprehensive compilation through a data mining procedures.
During the image processing phase, conventional libraries like OpenCV and Python's image analysis tools were harnessed to refine images for analysis. In contrast, image acquisition utilized established URL libraries in Python, facilitating direct access to original SOHO repository images and eliminating the need for local storage.
The computation of spectral parameters involved a fusion of standard Python libraries and tailored algorithms for specific attributes. This approach ensures precise computation of a diverse array of attributes crucial for comprehensive analysis of solar images
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