332 research outputs found

    Similarity effects of two types of adaptogens (transcutaneous electrical stimulation with the device “VEB” ® and using of bioactive Naftussya water) on the human body

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    Background. The studies of the Truskavetsian Scientific School of Balneology have shown that both the Naftussya bioactive water and the standard balneotherapy complex (Naftussya drink, ozokerite applications, mineral baths) exhibit the properties of adaptogens, similar to such ginseng and phytocompositions. At the same time, in the process of researching the influence of devices for transcutaneous electrical stimulation on the human body, we found that changes in the parameters of the neuro-endocrine-immune complex and metabolism also have an adaptogenic character. The purpose of this study is to find effects common to adaptogens of chemical and physical nature. Materials and Methods. The object of observation were 29 women 30-76 (50±13) y and 28 men 25-69 (48±13) y without a clinical diagnosis, but with the deviations from the norm in a number of parameters of the neuro-endocrine-immune complex as a manifestation of dysadaptation. Parameters of biophotonics, acupuncture points, EEG, HRV, immunity, metabolism, blood pressure and hormones levels before and after a four-day transcutaneous electrical stimulation session or one-week course of drinking of Naftussya water registered. Results. Screening revealed that 43 variables respond to the action of adaptogens according to the law of the initial level, at the same time, 4 initially elevated and 9 normal variables show further growth. Caused by adaptogens changes in 7 EEG and 7 HRV parameters determine favorable changes in 2 endocrine, 10 immune, 3 metabolic, 2 hemodynamic and 3 biophotonics parameters by 83,5%. Conclusion. The adaptogens both of chemical and physical nature, activating the receptors of the gut mucosa or the skin, respectively, have similar favorable effects on the parameters of the neuroendocrine-immune complex, metabolism, hemodynamics and biophotonics

    Features of Linguistic Gender Studies = Особливості лінгвістичних гендерних досліджень

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    Features of Linguistic Gender StudiesОсобливості лінгвістичних гендерних досліджень Yuliya MaslovaЮлія Маслова National University “Ostroh Academy”Національнийо університет «Острозька академія» Walery ZukowWalery Zukow Kazimierz Wielki University, BydgoszczUniwersytet Kazimierza Wielkiego, Bydgoszcz     Corresponding AuthorYuliya Maslova, candidate of philological sciences, associate professor of Chair documentation and information activities, National University "Ostroh Academy"E-mail: Yuliya Maslova [email protected] Юлія Маслова, кандидат філологічних наук, доцент кафедри документознавства та інформаційної діяльності Національного університету «Острозька академія»E-mail: Yuliya Maslova [email protected]  AbstractThis article describes the features of linguistic gender research, singled out key areas relevant to gender studies, gender analyzes the specific language, the theoretical analysis of the main stages of gender linguistics. Keywords: gender, linguistics, masculine, feminine, language, sex. ResumeУ статті описано особливості розвитку гендерних лінгвістичних досліджень, виокремлено основні релевантні напрями гендерних студій, проаналізовано гендерну специфіку мови, здійснено теоретичний аналіз основних етапів становлення гендерної лінгвістики. Ключові слова: гендер, лінгвістика, маскулінне, фемінне, мова, стать.

    Interleukins changes in blood of non-ethanol liver damage rats of different sex

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    Non-alcoholic liver disease is associated with liver injury, such as steatosis, steatohepatitis, fibrosis and cirrhosis. During their development, inflammation is occure and organs damage develops by help of cytokines influences. The intensity of injury depends on sex. The aim of the study was to evaluate changes of interleukins in the blood of male and female rats with hepatosis, hepatitis used by overdrinking of glucose. Material and methods of investigation. The experiments were performed on 60 male and 60 female outbred rats aged from four monthes (start of experiment). Animals were divided into five groups – control 1 (6 monthes old animals), control 2 (8 monthes old animals), glucose 2 monthes (3), glucose 4 monthes (4), and glucose 2+2 monthes (5). Determined in the blood serum Tumor Necrosis Factor Alpha (TNF-α), Interleukin 1 Beta (IL-1β), Interleukin 4 (IL-4), Interleukin 10 (IL-10). Results. In 3, 4 and 5 groups we determined increasing of proinflammatory interleukins. When comparing the results of 5 groups with 3 in male rats, lower values of anti-inflammatory interleukins were noted with a reliably insignificant difference in the content of pro-inflammatory interleukins. Interleukins changes were not detected in rats female between groups 5 and 3.When comparing 3 and 4 groups, an increase in TNF-α and IL-1β, a decrease in IL-4 and IL-10 both in males and in females were determing, which depended on the duration of glucose consumption. When comparing groups 5 and 4 in males rats, only TNF-α decreased, which can be regarded as a decrease in destructive processes when glucose consumption is stopped. In females, we see a decrease in TNF-α and IL-1β, an increase in IL-4 and IL-10, which may indicate a decrease in the effect of glucose or its long-term effect, since the results of groups 3 and 5 in female rats did not differ. Conclusion. An increase in the content of pro-inflammatory interleukins and a decrease in anti-inflammatory interleukins was detected after 2 months, 4 months of glucose use, which is maintained for 2 months after the cessation of its use only 2 months and depends on the duration of glucose use. In males, the inflammatory reaction is more than in females

    Glomerular filtration and diuresis are related to the state of lipids peroxidation in female rats exposed to water-salt loads accompanied by chronic stress

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    Background. It is known about the existence of close functional link between adequate working kidney nephrons and bone metabolism. Focused monitoring of renal function is able to provide substantial assistance in the organization of preventive measures against latently emerging osteoporosis. Activation of lipoperoxidation is known to inhibit glomerular filtration, whereas antioxidants prevent this. We set ourselves the goal of clarifying correlations between glomerular filtration, as well as tubular water reabsorption and daily diuresis, on the one hand, and lipoperoxidation parameters, on the other hand. Materials and Methods. Experiment was performed on 50 healthy female Wistar rats 240-290 g, both intact and exposed to water-salt loads. By the size of the diuresis and the level of creatinine in plasma and urine, glomerular filtration and tubular reabsorption were calculated. The plasma levels of diene conjugates and malondyaldehide as well as catalase of plasma and superoxide dismutase of erythrocytes were determined. The levels of the first three parameters determined in urine too. Results. In conditions of water-salt loads accompanied by chronic stress, glomerular filtration is downregulated by malondialdehyde and superoxide dismutase; diuresis is also downregulated by malondialdehyde, but upregulated by catalase. Lipoperoxidation parameters determine kidney function by 52,8%. Conclusion. The obtained data indicate the role of lipoperoxidation as a accompaniment of chronic stress in the regulation of kidney functions

    Health behaviors of patients with ischemic heart disease undergoing early cardiac rehabilitation in the age range of 45-60 years

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    Introduction and purpose of the work: Along with the development of civilization, civilization diseases appear, which take the form of the highest death rates, mainly in the field of cardiovascular diseases. It is largely related to the accumulation of negative consequences of improper health habits, as well as reduced physical activity. The aim of the study was to present the impact of health behaviors on the example of patients with ischemic heart disease treated with the CABG method, undergoing early cardiac rehabilitation at the "Równica" Health Resort in Ustroń, at the 2nd Cardiac Rehabilitation Department. Materials and methods: The study was conducted among 81 patients, after coronary artery bypass surgery (CABG), rehabilitated at the 2nd Department of Early Cardiac Rehabilitation at the "Równica" Health Resort in Ustroń. The research was conducted from 10.2021 to 02.2022. The Health Behavior Inventory (IZZ) according to Juszczyński and an own questionnaire were used for the research. Research results: According to the data analysis, Proper Eating Habits scored the highest, followed by Preventive Behavior and Positive Mental Attitude, and the lowest - Health Practices. Conclusions: Based on the analysis of the conducted research, it can be concluded that people with ischemic heart disease do not care for their health properly. Women and the elderly, as well as physically active people, fare better in this respect

    Changes of electrocardiograms and heart morphology of animals with different resistance to hypoxia under influences of stress

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    Stress is a process that increases a person’s adaptive capacity and leads to the various diseases, such as hypertension, coronary artery disease, heart attack, cardiac arrest, stroke, mental disorders such as depression and anxiety and even sudden death. Individual response to stress may depend on age, gender, features of autonomic regulation, state of the central nervous system, endocrine systems, higher nervous activity. With excessive stress, the work of internal organs is disturbed, in particular, the cardiovascular system. Determination of the damaging effect of stress on the cardiovascular system in individuals with different reactivity will contribute to the development of individual correction methods. The aim of the study was to analyze the changes in electrocardiograms (ECG) and morphological feachers after stress in animals with different resistance to hypoxia. Material and methods of investigation. Experiments were performed on 48 Wistar rats, with high and low resistance to hypoxia (HRH, LRH), aged 5–6 months. Animals were divided into two groups – control and experimental (after immobilization stress). Individuals with different resistance to hypoxia were selected by method of V. Ya. Berezovsky. Stress was modeled by three one-hour immobilization of rats, which were immobilized on their backs with an interval of 24 hours between each stressful episode. Investigation we did after 24 hours after third immobilization. Under anesthesia were registrated ECG and taken heart for morphological investigation. Sections were stained with hematoxylin and eosin. Results. In examining the ECG in control HRH and LRH animals, no significant difference in the analyzed ECG indicators was established. 24 hours after the last 1 hour three-time immobilization in HRH rats were noted an increase in heart rate, a decrease of the duration of the RR interval, a decrease of the amplitude of the R wave, an increase of QTc interval, an increase of the amplitude of the T wave, an increase in the deviation of the ST segment from the isoline. In LRH rats, stress caused an increase in heart rate, a decrease in the duration of the RR interval, a decrease in the duration of the PQ interval, a decrease in the amplitude of the R wave, an increase in the amplitude of the T wave, an increase in the deviation of the ST segment from the isoline. When comparing the parameters of НRH and LRH rats, in LRH were found a smaller amplitude of the P wave, a smaller amplitude of the R wave, a smaller value of the QTc interval, greater deviation of the ST segment from the isoline. Physiological changes on ECG can also connected with morphological feaches. Conclusions. Stress leads to changes in functional and histological properties of heart, which depends on resistance to hypoxia. In the ECG 24 hours after the last 1 hour three-time immobilization in HRH and LRH rats were noted an increase in heart rate, a decrease of the duration of the RR interval, a decrease of the amplitude of the R wave, an increase of the amplitude of the T wave, an increase in the deviation of the ST segment from the isoline. In HRH rats were also an increase of QTc interval, in LRH rats – a decrease in the duration of the PQ interval. Indxes changes were grater in LRH rats. Mophological changes was higher also in LRH animals
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