Therapeutic drug monitoring for antimicrobial agents for people living with HIV (TAP)

Abstract

The Therapeutic drug monitoring for antimicrobial agents for people living with HIV (TAP) project aims to determine the concentrations of selected antibiotics in people living with HIV and to assess how useful it is to monitor the amount of the antibiotics in blood while adjusting the dose. This study will enroll adults living with HIV receiving amoxicillin, azithromycin, ciprofloxacin, rifampicin, isoniazid, or ceftriaxone. Concentrations of these antibiotics will be measured, and for those on TB drugs, doses will be adjusted until the participant achieves suitable amounts of the drug in blood. We anticipate that the findings from this research will help us to know how much of the antibiotics is in the body and if people respond as expected to the treatment