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review journal article
oaioai:uis.brage.unit.no:11250/3196235

An isofagomine analogue with an amidine group in the 1,6-position

Authors
Publication date
1 January 2025
Publisher
The Royal Society
Doi

    Abstract

    The synthesis of an isofagomine analogue with an amidine group in the 1,6-position is described. Density functional theory calculations showed that this compound has a remarkably different charge distribution compared with isofagomine. This may explain why the amidine is a poor glycosidase inhibitor (IC50 > 50 µM against all tested enzymes) compared with isofagomine.publishedVersio

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    This paper was published in UiS Brage.

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