research article
Bone and Soft Tissue: Ewing-like sarcoma
Abstract
Ewing-like sarcoma is a recently defined subset of bone or soft tissue sarcomas. It is one of the pediatric small, round, blue cell tumors and is fusion gene-driven cancer. However, the driving fusions are distinct from that of the FET-ETS family rearrangements that define Ewing sarcoma (see separate entry for Ewing sarcoma)- Article
- Ewing-like sarcoma
- Tumors Section
- 12E7 Antigen/analysis/blood
- Humans
- Neoplasm Metastasis/physiopathology
- Proto-Oncogene Protein c-fli-1/analysis/blood
- Quality of Life/psychology
- RNA-Binding Protein EWS/analysis/blood
- Radiography/methods
- Risk Factors
- Sarcoma, Ewing/blood/*diagnosis/physiopathology
- Adolescent
- Adult
- Biomarkers, Tumor/analysis/*genetics
- Bone Neoplasms/chemistry/*genetics/pathology/therapy
- Child
- Child, Preschool
- Cyclin B/*genetics
- Disease Progression
- Female
- *Gene Fusion
- Genetic Predisposition to Disease
- Humans