<ORIGINAL ARTICLE>Experimental Study on Salivary Gland Scintigraphy with ^<99m>Tc-pertechnetate

Abstract

P(論文)In diagnosing salivary gland diseases, along with the remarkable progress of nuclear medicine, scintigraphic examinations are being utilized. On the other hand, sialographic diagnosis has been carried out from old time. But, in most cases, either scintigraphy or sialography has been used alone independently, and thus there have been very few papers reported on a comparison between the two. To study the fundamental relationship between scintigraphic findings and sialographic ones, scintigraphy and microsialography were carried out on the ligated parotid glands of rabbits. After ligation, comparisons were run on the 3rd day, 7th day, 10th day and 28th day. Pathological findings also were added. The results obtained were as follows; (1) Scintigraphic findings showed little changes in shape until the 3rd day after ligation, but, after the 7th day, a remarkable decrease of ^Tc-pertechnetate uptake was observed. (2) Microsialographic changes were observed in pararell with the uptake of ^Tc-pertechnetate. (3) Pathological findings definitely showed the relationship between scintigraphic findings and microsialographic findings.departmental bulletin pape