Purpose: The aim of the study was to compare the responses of pulmonary (V’O2pulm) and muscle (V’O2musc) oxygen uptake kinetics before (PRE) and after (POST) six weeks of endurance exercise training. Methods: Nine untrained individuals performed pseudo-random binary sequences work rate changes between 30 W and 80 W at PRE and POST training intervention. Heart rate (HR) and V’O2pulm were measured beat-to-beat and breath-by-breath, respectively. V’O2musc was estimated applying the approach of Hoffmann et al. (Eur J Appl Physiol 113: 1745–1754, 2013). Results: Maximal oxygen uptake showed significant increases from PRE (3.2 ± 0.3 L min−1) to POST (3.7 ± 0.2 L min−1; p 0.05). Conclusions: Discrepancies in the adaptations of the involved exercise induced physiological systems seem to be responsible for the observed significant alterations in maximal V’O2 after six weeks of the training intervention in contrast to no changes in the kinetics responses
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