Square-edge intraocular lens versus conventional round-edge intraocular lens in prevention of posterior capsule opacification: A randomized clinical trial

Abstract

Aim: To determine whether square-edge polymethyl methacrylate (PMMA) intraocular lens (IOL) is superior in preventing clinically significant posterior capsule opacification (PCO) and better visual outcome when compared with round-edge PMMA IOL in manual small-incision cataract surgery (MSICS). Settings and Design: Tertiary care hospital-based randomized controlled clinical trial. Materials and Methods: A randomized clinical trial of 1 year in which 128 patients were randomized into two groups to receive round-edge IOLs (Group A) or square-edge IOLs (Group B) after MSICS and followed up for 10 months; during follow-up, the best corrected visual acuity, grades, and type of PCO were documented. Statistical Analysis Used: Data analysis was done using chi-square test. Results: Out of 128 patients, the incidence of PCO was 83.6%, out of which 85.9% were in Group A and 81.2% were in Group B. Visual outcome was better in Group B, which was statistically significant (0.003). The fibrous type of PCO was the commonest type seen in the study irrespective of the group. There was less incidence of PCO in capsulorrhexis (with relieving incisions) and complete cortical cleanup cases. Difference in neodymium-doped yttrium aluminum garnet; Nd:Y3Al5O12 (Nd:YAG) laser capsulotomy rates were not statistically significant between the two groups (P = 0.784). Conclusions: This study showed that square edge PMMA IOLs had less clinically significant PCO rates and better visual outcome when compared to round-edge PMMA IOLs