Effect of Globus Pallidus internus stimulation on gait in multifocal dystonia: A case study

Abstract

A study was conducted to investigate the influence of deep brain stimulation (DBS) of the Globus Pallidus internus (GPi) on multifocal dystonia, called as clinical, spatio-temporal, and kinematic parameters of lower limbs during plain gait. The patient, 52 years old female without skeletal deformities, was recruited from the Center of Movement Disorder at the Department of Neuroscience, in Ferrara, Italy to conduct the investigations. Joint kinematics and spatio-temporal gait parameters were measured by means of 6 infrared cameras at 100 samples per second. Sixteen markers were attached to the subject's lower limbs and pelvis according to the Plug-in Gait protocol (PIG). The median values and confidence intervals of spatio-temporal parameters for the two sides and parameters for right and left side were reported