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MCL1 down-regulation plays a critical role in mediating the higher anti-leukaemic activity of the multi-kinase inhibitor Sorafenib with respect to Dasatinib.

By Secchiero P, Melloni E, Voltan R, Norcio A, Celeghini C and Zauli G.


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Topics: apoptosis, acute leukaemia, acute myeloid leukaemia
Year: 2012
DOI identifier: 10.1111/j.1365-2141.2012.09042.x
OAI identifier: oai:iris.unife.it:11392/1608666
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