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Transfusional therapy of hemodialyzed patient with anti-Cartwright \ud antibodies: case report and review of the literature

By Franchini M., Fabbian F., Piccoli P.L., Gandini G., Aprili G., Loschiavo C. and Lupo A.

Abstract

BACKGROUND: Red cell Cartwright antigen (Yta) is very common in the general \ud population therefore patients without red cell Cartwright antigen and with \ud anti-Yta alloantibodies due to previous exposure to the antigen are rare. \ud Report about clinical significance of Yta red cell alloantibodies in \ud hemodialysis (HD) patients are scarce. CASE REPORT: We report a cirrhotic \ud uremic patient with anti-Yta antibodies who received Yta positive red \ud cells. No adverse reactions nor hemolysis were detected. CONCLUSIONS: We \ud concluded that dialysis patients with anti-Yta antibodies could be safely \ud transfused with blood from Cartwright positive donors

Topics: blood transfusion, erythrocyte, renal replacement therapy, uremia
Year: 2004
OAI identifier: oai:iris.unife.it:11392/1400406
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