The World Health Organization (WHO) published the third edition of its guidelines for the safe use of wastewater, excreta and greywater in agriculture in September 2006. These new guidelines are intended to support the establishment of national standards and regulations. However, it is not straightforward for policymakers or practicing engineers to translate them into numerical values that are easy to implement. This chapter presents a practical interpretation of the main concepts of the new WHO guidelines and provides guidance on how to apply them in national settings. \u
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