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Detection of Transcription Factor Binding Sites

By Ondřej Hlávka

Abstract

Nowadays, it is very important to study gene expression mechanism in molecular biology. Gene expression is also regulated by sequence specific transcription factors which binds to regulatory regions of the genes. Searching for this specific sequences can be very problematic because transcription factor binding sites can be very degenerative. There are several possible methods that can be aplied to this problem. First part of this paper describes few algorithms for transcription binding sites search. Second part contains design and implementation of algorithm for searching binding sites of transcription factor p53

Topics: Transcription factor; vyhledávání TFBS; protein p53; Transkripční faktor; regulace genové exprese; TFBS searching; gene regulation
Publisher: Vysoké učení technické v Brně. Fakulta informačních technologií
Year: 2013
OAI identifier: oai:invenio.nusl.cz:236375
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