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Analysis of DNA Structure Elements

By Marek Knytl


The aim of this master's thesis is the design and implementation of tool trackAnalysis for statistical analysis of DNA structure elements. The positions of individual elements in genome are obtained in the form of the track, and with these positions the tool performs a set of analyzes, including randomness test of track, test examining distances between track and genes, detection of clusters and overlaps. The indivudual tests results can be linked together. The results will be displayed in the form of a list, a graph or a new annotation track. An important part of this thesis is also testing the resulting tool on a set of real data

Topics: transcription factor; Gene ontology; transkripční faktor; Annotation track; BED; Bioconductor; Anotační stopa; analýza stop; R; track analysis
Publisher: Vysoké učení technické v Brně. Fakulta informačních technologií
Year: 2013
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