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Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty

By Hance Clarke, Sara Pereira, Deborah Kennedy, Ian Gilron, Joel Katz, Jeffrey Gollish and Joseph Kay


BACKGROUND: Moderate to severe pain after total knee arthroplasty often interferes with postoperative rehabilitation and delays discharge from hospital. The present study examined the effects of a four-day postoperative gabapentin (GBP) regimen versus placebo on opioid consumption, pain scores and knee flexion, as well as adverse effects, after total knee arthroplasty

Topics: Medicine (General), R5-920
Publisher: Hindawi Limited
Year: 2009
DOI identifier: 10.1155/2009
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