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Imatinib in PDGFR positive malignant solitary fibrous tumour of the pleura

By Sarah Bigeni, Cynthia Jones and Joseph Galea


In 2013, two cases of malignant solitary fibrous tumours (MSFTs) were diagnosed in Malta. Both were inoperable at presentation. Both tumours expressed platelet-derived growth factor receptor (PDGFR) with no mutations and the tyrosine kinase inhibitor imatinib was prescribed. Nonetheless, treatment was not as effective as documented in previous case-reports

Topics: Malignant Solitary Fibrous Tumours, Imatinib, Pleura, PDGFR, Medicine, R
Publisher: IJCTO
Year: 2016
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