Skip to main content
Article thumbnail
Location of Repository

PLACENTAL GROWTH FACTOR AND CORONARY NEOANGIOGENESIS IN CORONARY HEART DISEASE

By M. V. Tulikov, O. P. Shevchenko, A. O. Shevchenko, A. V. Gagayev and V. V. Pavlov

Abstract

<p>Neoangiogenesis in coronary heart disease is a protective reaction aimed to improve ischemic myocardial perfusion, by increasing the number and size of arterial collaterals. Placental growth factor (PlGF) is one of the key peptides regulating angiogenic processes in atherosclerosis. In particular, a number of investigators have shown that injection of recombinant PlGF into the system or regional blood flow can stimulate neoangiogenesis. On the other hand, there is evidence confirming the involvement of PlGF in the progression of atherosclerosis and in the development of acute coronary syndrome. In this connection, the problem of investigating the efficiency and safety of possible use of PlGF preparations, as well as its place in the diagnosis of coronary heart disease and acute coronary syndrome remains urgent</p

Topics: плацентарный фактор роста, ишемическая болезнь сердца, острый коронарный синдром, прогноз, воспаление, неоангиогенез, Medicine, R
Publisher: ABV-press
Year: 2013
OAI identifier: oai:doaj.org/article:1949bb90028046a184c6cbef5ef0d854
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/2412-8775 (external link)
  • https://doaj.org/toc/1818-8338 (external link)
  • http://klinitsist.abvpress.ru/... (external link)
  • https://doaj.org/article/1949b... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.