Results of endoscopic treatment of primary vesicoureteral reflux at Children's Hospital Zagreb

Abstract

Vezikoureteralni refluks (VUR) je jedna od najčešćih patologija dječjeg urinarnog sustava i čest razlog posjeta dječjem kirurgu. Radi se o retrogradnom toku urina iz mokraćnog mjehura u uretere. U kombinaciji s infekcijom urinarnog sustava, kojoj su djeca oboljela od VUR-a podložnija, može dovesti do ožiljkavanja bubrežnog parenhima i u konačnici do smanjenja njegove funkcije , a u najtežim slučajevima i do bubrežnog zatajenja. VUR i do pet puta češće zahvaća djevojčice, iako se prenatalno i u prvoj godini života češće dijagnosticira u dječaka. Tipična klinička slika ne postoji, no učestale urinarne infekcije u dječjoj dobi svakako trebaju pobuditi sumnju na postojanje VUR-a. Prema smjernicama Međunarodnog povjerenstva za istraživanje refluksa, VUR klasificiramo u 5 stupnjeva. U skladu sa šarolikom kliničkom slikom, postoji i cijeli spektar dijagnostičkih metoda i terapijskih pristupa. Zlatni standard liječenja VUR-a je endoskopsko liječenje, koje je prvi put opisano 1981. godine i od onda se nastavilo razvijati. Na Klinici za dječju kirurgiju, Klinike za dječje bolesti Zagreb, VUR se liječi endoskopskim pristupom od 2003. godine. U ovom radu napravljena je kratka presječena retrospektivna analiza 66 pacijenata koji su 2012. i 2013. endoskopski liječeni na Klinici zbog primarnog VUR-a. Podaci su se prikupljali putem bolničkog informacijskog sustava. Dobiveni podaci se podudaraju s literaturom i potvrđuju visoku uspješnost endoskopskog pristupa u liječenju primarnog vezikoureteralnog refluksa.Vesicoureteral reflux (VUR) is one of the most common pathologies of the child's urinary system and a frequent reason for visiting pediatric surgeon. It is defined as a retrograde flow of urine from the bladder into the ureters. In combination with urinary tract infections, VUR can lead to renal scaring, hypofunction of the kidney and kidney failure. VUR can be up to 5 times more common in girls, even though prenatally and during the first year of life it is more often diagnosed in boys. There is no typical clinical presentation, but if urinary infections are frequent, they should raise suspicion for VUR. Depending on its severity, International Reflux Study Commitee classifies VUR into 5 categories. In line with the variety of clinical presentation, there is a whole spectrum of diagnostic methods and therapeutic approaches. The gold standard of VUR treatment is endoscopic treatment first described in 1981. At the Department of Pediatric Surgery of the Children's Hospital Zagreb, VUR has been treated endoscopicaly since 2003. In this paper, a short retrospective analysis of 66 patients treated endoscopicaly for primary VUR at the Department of Pediatric Surgery of the Children's Hospital Zagreb in 2012 and 2013 is made. The data was collected through the hospital information system. The data obtained correlates with the literature and show high success rate of endoscopic approach in the treatment of primary vesicoureteral reflux

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This paper was published in University of Zagreb Repository.

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