HAMLET binding to ?-actinin facilitates tumor cell detachment
Abstract
10.1371/journal.pone.0017179PLoS ONE63e1717- Article
- alpha actinin
- alpha actinin 1
- alpha actinin 4
- alpha lactalbumin
- beta1 integrin
- F actin
- focal adhesion kinase 1
- human alpha lactalbumin made lethal to tumor cell
- ion channel
- mitogen activated protein kinase 1
- small interfering RNA
- unclassified drug
- actin
- actinin
- beta1 integrin
- cell extract
- focal adhesion kinase
- HAMLET complex, human
- lactalbumin
- oleic acid
- peptide
- amino acid sequence
- article
- binding site
- cell adhesion
- cell proliferation
- cell structure
- cell survival
- cell viability
- controlled study
- enzyme phosphorylation
- human
- human cell
- immunoprecipitation
- in vitro study
- molecular mechanics
- polyacrylamide gel electrophoresis
- protein binding
- protein cross linking
- protein domain
- protein expression
- protein isolation
- protein localization
- protein protein interaction
- signal transduction
- tumor cell
- biological model
- cell adhesion
- cell death
- chemical structure
- chemistry
- drug effect
- enzymology
- metabolism
- molecular genetics
- neoplasm
- pathology
- protein analysis
- protein binding
- protein transport
- tumor cell line
- Actinin
- Actins
- Amino Acid Sequence
- Antigens, CD29
- Binding Sites
- Cell Adhesion
- Cell Death
- Cell Extracts
- Cell Line, Tumor
- Cell Survival
- Focal Adhesion Protein-Tyrosine Kinases
- Humans
- Lactalbumin
- Models, Biological
- Models, Molecular
- Molecular Sequence Data
- Neoplasms
- Oleic Acids
- Peptides
- Protein Binding
- Protein Interaction Mapping
- Protein Transport
- Signal Transduction