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MRI micelles self-assembled from synthetic gadolinium-based nano building blocks

By Andréj Babic, Vassily Vorobiev, Gregor Trefalt, Lindsey Crowe, Lothar Helm, Jean-Paul Vallée and Eric Allémann

Abstract

A synthetic nano building block endowed with amphiphilic properties and chelated gadolinium is presented. Spontaneous self-assembly into small 12 nm corona-core stealth Gd-micelles with inherently high gadolinium loading occurs in water. Gd-Micelles are a new blood pool contrast agent with high relaxivity for magnetic resonance imaging

Topics: info:eu-repo/classification/ddc/540, info:eu-repo/classification/ddc/615, info:eu-repo/classification/ddc/616.0757
Publisher: 'Royal Society of Chemistry (RSC)'
Year: 2019
DOI identifier: 10.1039/C8CC08875F
OAI identifier: oai:unige.ch:unige:126343
Provided by: Archive ouverte UNIGE
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