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Colloidal Nanocrystalline Luminophors Doped by Rare-earth Ions for Biological Testing

By A.V. Grigorova, V.K. Klochkov, N.S. Kavok and O.O. Sedyh


nReVO4:Eu3+ (Re Gd, Y, Sm, La) luminescent nanocrystals of different shape and size from 2 to\ud 300 nm have been synthesized. Luminescence of nReVO4:Eu3+ nanocrystals are effectively excited under\ud UV and visible irradiation. By means of luminescence microscopy and luminescence microspectroscopy it\ud has been revealed that spherical nanocrystals with an average diameter from 3 to 20 nm tend to accumulate\ud mainly in the isolated rat hepatocyte nuclei. Spherical nGdYVO4:Eu3+ nanocrystals are efficient inorganic\ud markers and can be used in systems of selective delivery of substances into the cell nucleus. When you are citing the document, use the following link

Topics: Nanoparticles, Luminescence, Cell, Hepatocyte nuclei, Intranuclear accumulation
Publisher: Sumy State University
Year: 2012
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