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MOESM8 of Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

By Raúl Pérez (6192611), Pablo Santamarina (5536325), Juan Tejedor (6192614), Rocío Urdinguio (3512183), Julio Álvarez-Pitti (6192617), Pau Redon (6192620), Agustín Fernández (243816), Mario Fraga (2008762) and Empar Lurbe (3472910)

Abstract

Additional file 8: Table S4. Chromatin state enrichment analysis of 0→5 and 5→10 dmCpGs. Enrichments were calculated based on differences between the dmCpGs obtained in each of the analyses and the hg19 chromatin segmentation regions (ChromHMM, 18 states) obtained from Roadmap and ENCODE consortia. A custom LOLA database including information related to the chromatin states in the different tissues/cell lines and corresponding array backgrounds were used for the correct enrichment calculation

Topics: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Cancer, Inorganic Chemistry, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Epigenetics, DNA methylation, Histone modification, Aging, Newborn, Longitudinal
Year: 2019
DOI identifier: 10.6084/m9.figshare.7569818.v1
OAI identifier: oai:figshare.com:article/7569818
Provided by: FigShare
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