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Furan synthesis through AuCl3-catalysed cycloisomerisation of β-alkynyl β-ketoesters

By Arantxa Rodriguez and Wesley J. Moran


AuCl3 efficiently catalyses the cycloisomerisation of readily available β-alkynyl β-ketoesters to generate trisubstituted furans. The substrate scope is wide and the reaction is high yielding and operationally simple

Topics: QD
Publisher: Elsevier
Year: 2011
DOI identifier: 10.1016/j.tetlet.2011.03.086
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