Carbon nanofiber electrode array for electrochemical detection of dopamine using fast scan cyclic voltammetry

Abstract

A carbon nanofiber (CNF) electrode array was integrated with the Wireless Instantaneous Neurotransmitter Concentration Sensor System (WINCS) for the detection of dopamine using fast scan cyclic voltammetry (FSCV). Dopamine detection performance by CNF arrays was comparable to that of traditional carbon fiber microelectrodes (CFMs), demonstrating that CNF arrays can be utilized as an alternative carbon electrode for neurochemical monitoring.The authors thank Ramsey Stevens of Carbon Design Innovations, Inc. for the use of a CCB AFM probe. This work was supported by NIH (K08 NS 52232 award to KHL), the Mayo Foundation (2008-2011 Research Early Career Development Award for Clinician Scientists to KHL) and NASA Ames Research Center