An Efficient, Selective, and Reducing Agent-Free Copper Catalyst for the Atom-Transfer Radical Addition of Halo Compounds to Activated Olefins

Abstract

Efficient and selective ATRA reactions of CCl4, CBr4, TsCl (Ts = tosyl), or Cl3CCO2Et with activated olefins (styrene, methyl methacrylate, n-butyl methacrylate, tert-butyl methacrylate) using the TptBuCu(NCMe) complex as a catalyst have been achieved in the absence of any reductant and with low catalyst loadings