Copper-Catalyzed Ficini [2 + 2] Cycloaddition of Ynamides

Abstract

The Ficini [2 + 2] cycloaddition using N-sulfonyl-substituted ynamides is described, featuring the utility of CuCl2 and AgSbF6 as catalysts. This work represents the first successful example of ynamides participating in a thermal [2 + 2] cycloaddition with enones

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The Francis Crick Institute

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Last time updated on 16/03/2018

This paper was published in The Francis Crick Institute.

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