<p><b>Introduction</b></p>
<p>With the intent of improving transparency in clinical research, the
International Committee of Medical Journal Editors (ICMJE) established
guidelines in 2005 regarding prospective clinical trial registration. This
action worked to address bias related to selective outcome reporting in the
medical literature. The objective of this study was to assess and characterize
the quality of registration of clinical trials appearing in shoulder
arthroplasty-related medical journals.</p>
<p><b>Methods</b></p>
<p>All randomized trials involving human subjects, pertaining to shoulder
arthroplasty, published between July 1, 2005 and December 31, 2015, and indexed
in either PubMed or SportDISCUS were analyzed. We assessed the prevalence of
registration, the timing of registration relative to patient enrollment
periods, and the variable rates of orthopedic journal compliance with ICMJE and
Food and Drug Administration clinical registration standards for our study.</p>
<p><b>Results</b></p>
<p>Of the 382 articles identified, 345 (90.3%) were excluded due to
failure to meet inclusion criteria. From the remaining 37, only 12 (32.4%)
studies were found to be registered in a trial registry. Ten (10/12, 83.3%) of
these provided their registration information within the body of the article.
None of the included studies from ICMJE-recognized journals were registered.
From 34 included studies from non-ICMJE recognized journals, 12 (35.3%) were
registered.</p>
<p><b>Conclusion</b></p>
<p>The level of compliance with clinical trial registration guidelines in
the decade since their release among shoulder arthroplasty trials in orthopedic
journals is poor. Given the importance of the issue, the prevalence of the
problem, and the fact that many other medical specialties have already made
efforts to improve ICMJE compliance, further work on the part of orthopedic
surgery journal authors and editors is needed to ensure the publication of
unbiased results. </p>
<p><b>Trial
Registration: </b>UMIN000022487</p
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