Overview of Interferon: Characteristics, signaling and anti-cancer effect
- Publication date
- 2017
- Publisher
Abstract
<small>Interferons are multifunctional cytokines widely used in clinical
settings as an anti-viral drug. In addition, interferon’s exhibit
anti-cancer and anti-bacterial effects. Nearly two thousand papers
related to interferon are published each year, which illustrates the
importance placed by researchers on the study of interferon. This review
focuses on recent advances in the study of interferon, particularly in
the areas of its mechanism of anti-cancer effect and signal
transduction. We also describe the tumor resistance to interferon and
the side-effect of interferon-based therapy, which leads to an
expectation of future research of interferon.</small