Synthesis of carbohydrate-conjugated azaphthalocyanine complexes for PDT

Abstract

A series of azaphthalocyanine (AzaPc) complexes conjugated with one or two carbohydrate groups for photodynamic therapy (PDT) were synthesized by the alkyne-azide click chemistry reaction with previously-developed AzaPc complexes incorporating the bomane group. (C) 2015 Elsevier Ltd. All rights reserved.This work was supported by the Technology Innovation Program (No. 10047759, Development of tetra-pyrrole type for Color, light-emitting, detecting Devices) funded by the Ministry of Trade, Industry & Energy (MI, Korea)

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