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Synthesis, Structure and Cytotoxicity of 3-C, N, S, Se Substituted Benzo[B]Selenophene Derivatives

By P. Arsenyan, E. Paegle, Sergejs Beļakovs, I. Shestakova, E. Jaschenko, E. Domracheva and J. Popelis


Synthesis, molecular structure and cytotoxic activity of a series of 3-C, N, S, Se substituted benzo[b]selenophene derivatives on human fibrosarcoma HT-1080, mouse hepatoma MG-22A, and mouse fibroblasts 3T3 cell lines are described. The correlation between compound LD(50) 3T3 fibroblast cell line and HT-1080 morphology was shown

Topics: Arylation; Amination; Benzo[b]selenophene; Cytotoxic activity; Morphology; Selenium; X-ray
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