Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function

Abstract

This work was supported by funding from the ETH Domain for the Blue Brain Project and the Laboratory of Neural Microcircuitry. The Blue Brain Project's IBM BlueGene/Q system, BlueBrain IV, is funded by the ETH Board and hosted at the Swiss National Supercomputing Center (CSCS). MS was supported by the NCCR Synapsy grant of the Swiss National Science Foundation. Partial support for PD was provided by the GUDHI project, supported by an Advanced Investigator Grant of the European Research Council and hosted by INRIA. We thank Eilif Muller for providing input on the analysis, Magdalena Kedziorek for help with proving maximality in directed cliques, Gard Spreemann for help with the analysis of the C. elegans connectome, and Taylor H. Newton for helpful discussions about statistical methods.Peer reviewe