French validation of the barriers to access to care evaluation (BACE-3) scale.

The aim of this study was to develop and evaluate a French version of the Barriers to Access to Care Evaluation (BACE-3) scale that is tailored to the socio-cultural and language setting of the study. The translation of the BACE-3 into French and its validation were the two key components of this psychometric investigation. An online survey was created and circulated to French-speaking participants who volunteered to participate in the study. For all translated questions, the reliability analysis key results (Cronbach's alpha and McDonald's Omega) were both>0.95, which is an excellent reliability value. The BACE-3 items were shown to be positively related to one another, implying excellent validity. Results of exploratory and confirmatory factor analyses showed that all stigma-related items were loaded under the same factor. The BACE-3 has been validated in French, and its psychometric qualities have been thoroughly evaluated and found to be excellent

Refining the role of presurgical PET/4D-CT in a large series of patients with primary hyperparathyroidism undergoing [18F]Fluorocholine PET/CT.

4D-CT has garnered attention as complementary imaging for patients with primary hyperparathyroidism (pHPT). Herein we evaluated a diagnostic strategy using [ <sup>18</sup> F]Fluorocholine Positron Emission Tomography/Computed Tomography (PET/CT), followed by 4D-CT integrated into PET/4D-CT after negative/inconclusive PET/CT results in a single-center retrospective cohort of 166 pHPT patients who underwent parathyroidectomy after [ <sup>18</sup> F]Fluorocholine PET/4D-CT. PET/CT and 4D-CT images were interpreted by three nuclear medicine physicians and one expert radiologist. Pathological findings were documented, and concordance rates were assessed. PET/CT results were categorized as positive/negative, with positive cases rated on a 3-level certitude scale: low, moderate, high. Inconclusive cases included low/moderate positivity. The added value of PET/4D-CT was assessed for negative/inconclusive cases through joint reading. PET/CT lesion-based analysis showed almost perfect interobserver concordance (Cohen's kappa >.8). Across the cohort, PET/CT had a sensitivity of 83%, specificity of 97%, PPV of 90% and NPV of 94%. For 4D-CT, these values were sensitivity: 53%, specificity: 84%, PPV: 56% and NPV: 82%. PET/CT was significantly more accurate than 4D-CT. Among 44 patients with negative/inconclusive results, PET/CT had sensitivity: 60%, specificity: 91%, PPV: 71% and NPV: 86%. In the same patients, sensitivity and specificity of the sequential diagnostic algorithm increased to 80% and 97%, showing significantly better global accuracy (92% vs. 83%) than standard PET/CT. We support a personalized imaging algorithm for pHPT, placing [ <sup>18</sup> F]Fluorocholine PET/CT at the forefront, followed by 4D-CT integrated into PET/4D-CT in the same imaging session for negative/inconclusive results. When PET/CT results are clearly positive, the additional sensitivity benefit of 4D-CT is minimal

Vaccins contre la dengue, le temps de l’optimisme prudent ? [Dengue vaccines, a time for cautious optimism?]

Vaccine could take a central role in the strategy to reduce the burden of dengue. The development of an effective and safe vaccine must address various immunological challenges. Several vaccines are currently in development. To date, two live-attenuated vaccines have been deployed. Both have an effectiveness that varies depending on the serotypes. The deployment of the Dengvaxia vaccine, which began in 2015, was marked by a major safety alert leading to its use being restricted to previously dengue-seropositive people over 9 years old. The Qdenga vaccine is currently being deployed. There is for now insufficient data to ensure its safety in seronegative people. Some travelers, who have previously been infected with dengue, are a group for whom a vaccination recommendation applies

Écrans et adolescence : quels enjeux pour la Génération Z ? [Screens and adolescence: what issues for the Z generation?]

Digital media and screens are ubiquitous in the daily lives of adolescents. The screen-addicted portrait of young people has gained public attention, and health professionals are often consulted about the impact of screen use on teenagers' physical and mental health. Scientific evidence suggests that screen use is associated with risks and benefits that need to be weighed up in a nuanced way. This paper takes a critical look at the issue of screen time and at the models for understanding a problematic screen use. These considerations underline the importance of adopting a contextual understanding of screen use in adolescence

Assessing the health risks associated with the usage of water-atomization shower systems in buildings.

In the context of climate change policies, buildings must implement solutions to reduce energy and water consumption. One such solution is showering with water atomization showerheads, which can significantly reduce water and energy usage. However, the lack of risk assessment for users' health has hindered the widespread adoption of this technology. To address this gap, we assess the risk of spreading bacteria, in particular the pathogenic bacterium Legionella pneumophila, from shower hose biofilms of different ages grown under controlled or uncontrolled conditions considering different levels of water hardness, during showering using water atomization showerheads (ECO) or continuous flow showerheads (STA). We compared the aerosol and bioaerosol emission - total, viable and cultivable - during a 10 min shower event between the two shower systems. We showed that the water-atomization showerhead emitted slightly more nanoparticles smaller than 0.45 µm and slightly fewer particles larger than 0.5 µm than the continuous flow showerhead. Additionally, ECO showerheads emitted fewer cultivable bacteria than STA, regardless of the biofilm's age or growth conditions. When Legionella pneumophila was detected in biofilms, ECO showerheads released slightly less cultivable Legionella in the first flush of shower water compared to the STA, ranging from 6.0 × 10 <sup>2</sup> to 1.6 × 10 <sup>4</sup> CFU·L <sup>-1</sup> . However, cultivable L. pneumophila was not detected in the aerosols emitted during showering with either showerhead. These findings suggest that emerging water-drop emission technologies might affect human exposure to aerosols differently than traditional systems, emphasizing the importance of assessing the health risks associated with any new shower system. Additionally, these findings provide valuable insights for achieving a balance between water and energy conservation

Nuove prospettive su intertestualità e studi della ricezione. Il Rinascimento italiano

Questo volume raccoglie una serie di contributi dedicati al problema dell’intertestualità e degli studi della ricezione, un ambito della ricerca letteraria da sempre privilegiato e tuttavia variegato e sfuggente. Infatti, nonostante nel tempo a un’intensa attività di scavo e individuazione delle fonti e dei rapporti testuali si sia affiancato un buon numero di riflessioni teoriche, i due ambiti (pratico e astratto) sono rimasti per lo più separati, nel caso dell’italianistica anche in ragione di un’evidente resistenza alle formulazioni teoriche. I lavori qui presentati cercano di superare tale spaccatura offrendo una riflessione sull’eredità critica (Pasquali, Conte, Bachtin, Kristeva, Segre per fare solo alcuni nomi) e nuove proposte di metodo – non di teoria – a partire dal lavoro svolto sui testi del Rinascimento italiano, forse l’epoca per la quale più si avverte la necessità di un approccio rinnovato alla questione. Saggi di Amelia Juri, Andrea Cucchiarelli, Giorgio Forni, Gabriele Baldassari, Irene Fantappiè, Andrea Salvo Rossi, Alessandro Carlomusto, Tommaso Forni, Elisabetta Olivadese, Selene Vatteroni, Martina Caterino, Jonathan Schiesaro

Comparison of student nurses' expectations and newly qualified nurses' experiences regarding clinical practice: A secondary analysis of a cross-sectional survey.

To compare student nurses' expectations and newly qualified nurses' experiences regarding clinical practice in Switzerland 1 year after graduation. A secondary explorative analysis of a cross-sectional survey. The data were sourced from the Swiss National Graduate Survey of Health Professionals covering six universities of applied sciences between 2016 and 2019, with information on three cohorts of bachelor student nurses, with a 1-year follow-up between each year. The participants were 533 bachelor-prepared nursing graduates. The student nurses' overall expectations included the following top two prioritized aspects: 'contributing to something important' and 'adequate time to spend with patients'. Newly graduated nurses' clinical practice experiences demonstrated that not all expectations were met 1 year after graduation. The largest gaps were found in 'adequate time to spend with patients', 'work-life balance' and experiencing 'good management'. The most crucial expectation gaps are related to having sufficient time to spend with patients and a good work-life balance. The most important result is whether there is a shortage of places for nurses to work rather than the oft-cited shortage of nurses. The expectations of Swiss newly qualified nurses can be better met by an assessment in the first year about which individual perceptions of workplace characteristics cause them to make choices to change something about their work, affect their job satisfaction or influence their intention to stay. Few of the student nurses' expectations were met 1 year after graduation, therefore Swiss healthcare institutions should improve needs assessments to strengthen the nurse workforce starting early in employment. The results underscore the importance of a constructive management culture, such as that in magnet hospitals in the United States which underpins the philosophy of changing in nursing. The results can be used internationally as a benchmark and as a basis for introducing potential interventions for nurse retention. This study was reported following the Standardized Reporting of Secondary Data Analyses Checklist. There were no patient or public contributions. This study has not been registered