Hydrodynamic effects of flood regulation in the Venice Lagoon

Dataset for the hydrodynamics in the Venice Lagoon under different flood regulation scenario

Data set for: Fault zone rocks associated with the reservoir-triggered seismicity of the Koyna-Warna area (India)

Chemical analyses of major elements in chlorite and calculated structural formulae, octahedral vacancies and occupancies and temperature of the trioctahedral chlorite

2DES data on the main light-harvesting complex from Chromera velia (C. velia) (CLH) and its far-red adapted oligomeric analogue (FR-CLH)

Each dataset consists in a complex struct (in matlab format) which includes reph, nonreph and purely absorptive dat

CASR gene polymorphisms in primary hyperparathyroidism: genetic susceptibility and clinical variability

Purpose: This study investigates the role of CASR gene polymorphisms (A986S, R990G, Q1011E) in PHPT genetic susceptibility and its clinical variability. The aim is to evaluate the prevalence of these polymorphisms in patients with sporadic PHPT and their impact on clinical course, biochemistry, and histological features. Methods: 106 patients underwent clinical and anamnestic evaluations, focusing on major PHPT complications, as well as biochemical analyses of blood and urine. Genetic testing was conducted for CASR gene polymorphisms. Histological data were available for 68 patients who underwent parathyroidectomy. Results: The sample included 83 women and 23 men; mean age at diagnosis was 54.5 years. 55 patients carried CASR gene polymorphisms, while 51 were wild-type. Prevalence rates of polymorphisms were consistent with data for the Caucasian population, with A986S being the most common (31%). No significant associations were found between polymorphisms and increased levels of ionized calcium or other blood phospho-calcium metabolism parameters. However, 24-hour urinary calcium levels were higher in patients with polymorphisms (p=0.0185), particularly in those older than 50 years (p=0.030) and with the A986S variant. Hypercalciuria was predictive of CASR polymorphism presence (OR = 2.76, p = 0.003). No significant association with PHPT complications, such as renal calculi or bone involvement, was confirmed. Histological data revealed no clear links between polymorphisms and more aggressive variants. Conclusion: CASR gene polymorphisms are associated with hypercalciuria but do not significantly influence age of onset or clinical phenotype in PHPT. Genetic analysis may be useful in selected cases to better understand individual clinical profiles

Role of postural test in differentiating primary aldosteronism from low renin hypertension

Background: The diagnostic accuracy of screening procedures and confirmatory tests is suboptimal to differentiate primary aldosteronism (PA) among patients with low-renin hypertension (HTN) is challenging. Our aim was to assess the role of postural stimulation test (PST, previously used for PA subtyping) in differentiating PA from low-renin HTN. Patients and methods: Clinical and endocrine data in clinostatic position (CP) and orthostatic position (OP) were evaluated in 190 hypertensive patients: 80 PA and 110 low-renin HTN. Multivariate techniques were computed: Principal Component Analysis (PCA), Partial Least Square-Discriminant Analysis (PLS-DA) and k-means clustering. Results: PST response showed 56/190 patients with suppressed renin levels in CP and OP (54/56 were PA), 56/190 with de-suppression of renin from CP to OP (45/56 were low-renin HTN), and 78/190 with renin measurable in CP and OP. Increased potassium and measurable renin in OP were predictors of low-renin HTN. Cluster analysis distinguished PA from low-renin: Cluster 2 included 104/110 low-renin HTN; Cluster 1 PA patients showed a higher frequency of suppressed renin levels at baseline and during PST (100% in CP and 95% in OP, respectively). Cluster 1 low-renin HTN patients had lower potassium and a higher frequency of suppressed renin levels at diagnosis and during PST, compared to Cluster 2. PLS-DA and PCA confirmed that renin in OP, renin response to PST and presence of hypokalemia were the most relevant parameters for distinguishing PA from low-renin HTN. Conclusion: Renin response during PST can be used to exclude PA among patients with low-renin HTN

Funds Reports

Details of equity and bond investments of the 20 largest funds (as at 31/12/2024) ex-Article 8 SFDR: compulsory annual or semi-annual report collection (latest available at date of submission

Teaching Capitalism. The role of schools of economic thought

The datasets in the repository allow a full understanding of the methodology used in the article. In particular, 1) they allow an analysis of the terms identifying the schools of thought introduced in the paper; 2) they allow a complete overview of the analyses of the lexical time series

Additive effects of multiple photoprotective mechanisms drive efficient photosynthesis under variable light conditions

Data for publication Summary Statement: This study in Physcomitrium patens shows that multiple photoprotective mechanisms regulating photosystems I and II have a synergic role in maintaining photosynthetic efficiency and growth under high, fluctuating light conditions

Formulation and optimization of alkali-activated regolith foams for lunar construction: assessing the role of the amorphous phase

Supporting experimental and numerical data for academic paper related to the GLAMS projec

Non-perennial, yet predictable: Hierarchical Stream Activation Enables the Prediction of Channel Network Dynamics in Sporadically Monitored Catchments - DATA

Data collected on the monitored nodes of Focobon and Valfredda catchments. The information collected are about node's ID, length, persistency and surveyed status on a specific date