Physical activity participation in Australians with multiple sclerosis: associations with geographical remoteness

Purpose Physical activity (PA) participation offers many benefits for persons with multiple sclerosis (MS). Persons with MS are significantly less active than the general population; however, there is insufficient evidence regarding the association between geographical remoteness and PA participation in persons with MS. We identify PA levels across levels of rurality in an Australian MS population. Materials and methods The Australian MS Longitudinal Study collects regular survey data from persons with MS in Australia, including demographic, clinical, and health behavioural data. Physical activity engagement was identified with the International Physical Activity Questionnaire-short form and geographical remoteness was identified from participants’ postcode using the Access and Remoteness Index for Australia. Hurdle regression analysis examined the relationship between remoteness and PA participation, and level of PA, after controlling for confounding. Results Data from 1260 respondents showed that 24% of persons with MS did not participate in any PA. Remoteness was not associated with the participation in any PA (OR 1.04; 89% highest density probability interval (HDPI) estimate 0.88, 1.22). Amongst those with any PA (n = 960), those living in more remote areas had, on average, higher levels of PA (RR 1.21; 89% HDPI estimate 1.11, 1.34). Conclusions Physical activity promotion does not need to differ based on geographical location

Endothelial biomarkers of thrombosis in critically ill patients with acquired coagulopathy: A prospective cohort study

Background: It remains largely unknown whether endothelial biomarkers can be used to predict thromboembolism in critically ill patients with an acquired coagulopathy. Materials & methods: The ability of syndecan-1, P-selectin and microRNA expressions to predict thromboembolism were assessed in 40 critically ill coagulopathic patients. Results: The area under the receiver operating characteristic curves for syndecan-1, P-selectin and the four differentially expressed microRNAs – determined by real-time qPCR analysis – to predict thromboembolism (n = 10, 25%) were 0.71 (95% CI 0.52–0.89), 0.73 (95% CI 0.52–0.95) and >0.80, respectively. Syndecan-1 and P-selectin concentrations were also significantly correlated with one another (R = 0.41, p = 0.008). Conclusion: Endothelial function biomarkers, including endothelial microRNA expressions, were associated with subsequent thromboembolism in critically ill patients who had a deranged coagulation profile

How does biochar aging affect NH3 volatilization and GHGs emissions from agricultural soils?

Biochar has been considered as a potential tool to mitigate soil ammonia (NH3) volatilization and greenhouse gases (GHGs) emissions in recent years. However, the aging effect of biochar on soils remains elusive, which introduces uncertainty on the effectiveness of biochar to mitigate global warming in a long term. Here, a meta-analysis of 22 published works of literature with 217 observations was conducted to systematically explore the aging effect of biochar on soil NH3 and GHGs emissions. The results show that, in comparison with the fresh biochar, the aging makes biochar more effective to decrease soil NH3 volatilization by 7% and less risk to contribute CH4 emissions by 11%. However, the mitigation effect of biochar on soil N2O emissions is decreased by 15% due to aging. Additionally, aging leads to a promotion effect on soil CO2 emissions by 25% than fresh biochar. Our findings suggest that along with aging, particularly the effect of artificial aging, biochar could further benefit the alleviation of soil NH3 volatilization, whereas its potential role to mitigate global warming may decrease. This study provides a systematic assessment of the aging effect of biochar to mitigate soil NH3 and GHGs, which can provide a scientific basis for the sustainable green development of biochar application

Mobile phones are hazardous microbial platforms warranting robust public health and biosecurity protocols

Advancements in technology and communication have revolutionised the twenty-first century with the introduction of mobile phones and smartphones. These phones are known to be platforms harbouring microbes with recent research shedding light on the abundance and broad spectrum of organisms they harbour. Mobile phone use in the community and in professional sectors including health care settings is a potential source of microbial dissemination. To identify the diversity of microbial genetic signature present on mobile phones owned by hospital medical staff. Twenty-six mobile phones of health care staff were swabbed. DNA extraction for downstream next generation sequencing shotgun metagenomic microbial profiling was performed. Survey questionnaires were handed to the staff to collect information on mobile phone usage and users’ behaviours. Each of the 26 mobile phones of this study was contaminated with microbes with the detection of antibiotic resistance and virulent factors. Taken together the sum of microbes and genes added together across all 26 mobile phones totalised 11,163 organisms (5714 bacteria, 675 fungi, 93 protists, 228 viruses, 4453 bacteriophages) and 2096 genes coding for antibiotic resistance and virulent factors. The survey of medical staff showed that 46% (12/26) of the participants used their mobile phones in the bathroom. Mobile phones are vectors of microbes and can contribute to microbial dissemination and nosocomial diseases worldwide. As fomites, mobile phones that are not decontaminated may pose serious risks for public health and biosecurity

Reap the crop wild relatives for breeding future crops

Crop wild relatives (CWRs) have provided breeders with several 'game-changing' traits or genes that have boosted crop resilience and global agricultural production. Advances in breeding and genomics have accelerated the identification of valuable CWRs for use in crop improvement. The enhanced genetic diversity of breeding pools carrying optimum combinations of favorable alleles for targeted crop-growing regions is crucial to sustain genetic gain. In parallel, growing sequence information on wild genomes in combination with precise gene-editing tools provide a fast-track route to transform CWRs into ideal future crops. Data-informed germplasm collection and management strategies together with adequate policy support will be equally important to improve access to CWRs and their sustainable use to meet food and nutrition security targets

The impact of different weed management systems on weed flora and dry biomass production of barley grown under various barley-based cropping systems

Weeds are among the major issues responsible for reduction in yield and profit in any crop production system. Herbicides are the easiest and quickest solution of weeds; however, their frequent use exert negative consequences on environment, human health, and results in the evolution of herbicide-resistant weed species. Due to these reasons, alternative weed management methods that are less harmful to environment and human health are needed. This two-year study evaluated the impact of different weed management options, i.e., false seedbed (FS), allelopathic water extracts (AWE), chemical control (CC), weed-free (WF) weedy-check (WC) on weed spectrum in various barley-based cropping systems, i.e., fallow-barley (FB), maize-barley (MB), cotton-barley (CB), mungbean-barley (M*B), and sorghum-barley (SB). Data relating to density, diversity, and biomass production of weed species prevailing in the studied cropping systems were recorded. Interactive effect of weed management methods and barley-based cropping systems significantly altered weed diversity, and densities of individual, broadleaved, and grassy weeds. A total 13 weed species (ten broadleaved and three grass) were recorded during both years of study. The highest dry biomass, diversity, and density of individual, broadleaved, and grassy weeds were noted in WC treatment, whereas WF treatment resulted in the lowest values of these traits. Chemical control resulted in the highest suppression of weed flora and improved dry biomass production of barley followed by AWE. The SB cropping system with CC or AWE resulted in the least weed flora. The M*B cropping system with CC or AWE produced the highest dry biomass of barley. It is concluded that including sorghum crop in rotation and applying AWE could suppress weeds comparable to herbicides. Similarly, including mungbean in rotation and applying AWE could increase dry biomass production of barley. In conclusion, herbicides can be replaced with an eco-friendly approach, i.e., allelopathy and inclusion of sorghum crop could be helpful in suppressing weed flora

Risk management and organisational performance in the Indonesian public sector: An empirical study

Issues surrounding the real benefits of risk management and the factors that can support successful risk management systems in the public sector are still relevant topics discussed by accounting scholars. However, most risk management research in the public sector focuses on the experiences of developed countries. To fill this gap in the literature, this quantitative study uses a survey to investigate the relationship between risk management systems and organisational performance in public sector organisations in Indonesia, a developing country. It concurrently explores transformational leadership, internal audit activities, public service motivation and business process improvement as elements that may influence the original relationship between risk management systems and organisational performance on these organisations. A final sample of 202 usable questionnaires was obtained and analysed using Partial least squares (PLS) path modelling to test the hypotheses using SmartPLS 3.0 software. PLS path analysis involved a main analysis of all usable samples and an additional multigroup analysis. Empirical evidence in this study suggests that transformational leadership and internal audit activities significantly influence risk management systems. Risk management system, in turn, significantly influences organisational performance through the mediating effect of business process improvement. Public service motivation serves as a mediator for the relationship between risk management system and business process improvement. However, the mediation effect of public service motivation is weak. The results of multigroup analysis revealed that organisation size does not moderate any paths in the model. Perceived risk management budget sufficiency significantly moderates the relationship between transformational leadership and risk management system and the relationship between risk management system and organisational performance. Perceived uncertainty level significantly moderates the relationship between risk management system and business process improvement. Thus, this study expands the discussion related to the complex relationship between a risk management system and organisational performance in a developing country’s public sector. The findings of this study provide practical implications for leaders and risk management practitioners in the public sector, particularly in the Indonesian context. This study also measured the risk management system and public service motivation as second-order formative constructs; these are considered new to the existing literature. However, the structured questionnaire used in this study restricted the depth of data collected; the use of a cross-sectional design limited the ability of this study to extensively examine the cause-and-effect relationships that can be identified in a longitudinal design. Nevertheless, these limitations are justifiable because the hypotheses of this study required answers for scope, rather than depth. Further, the use of moderating variables, which are examined in multigroup analysis, strengthened the cross-sectional design in this study

Flies, maggots and methamphetamine: how insects can reveal drugs and poisons at crime scenes.

The oldest book of zoology was published on clay tablets more than 3,600 years ago, and reported the names of 396 types of wild animals known at the time. Ten of them were different kinds of fly..

Novel deep learning approach to model and predict the spread of COVID-19

SARS-CoV2, which causes coronavirus disease (COVID-19) is continuing to spread globally, producing new variants and has become a pandemic. People have lost their lives not only due to the virus but also because of the lack of counter measures in place. Given the increasing caseload and uncertainty of spread, there is an urgent need to develop robust artificial intelligence techniques to predict the spread of COVID-19. In this paper, we propose a deep learning technique, called Deep Sequential Prediction Model (DSPM) and machine learning based Non-parametric Regression Model (NRM) to predict the spread of COVID-19. Our proposed models are trained and tested on publicly available novel coronavirus dataset. The proposed models are evaluated by using Mean Absolute Error and compared with the existing methods for the prediction of the spread of COVID-19. Our experimental results demonstrate the superior prediction performance of the proposed models. The proposed DSPM and NRM achieve MAEs of 388.43 (error rate 1.6%) and 142.23 (0.6%), respectively compared to 6508.22 (27%) achieved by baseline SVM, 891.13 (9.2%) by Time-Series Model (TSM), 615.25 (7.4%) by LSTM-based Data-Driven Estimation Method (DDEM) and 929.72 (8.1%) by Maximum-Hasting Estimation Method (MHEM)

Noticing soil in early childhood: Cultivating the arts of attention in the anthropocene

Soil is crucial for earthly ongoingness, yet it is frequently overlooked or ignored by humans. This presentation will share early insights from a participatory research project exploring child-soil relations in Perth, Western Australia that is informed by the philosophy and practices of the educational project of Reggio Emilia. The study seeks to cultivate attentiveness to soil through aesthetic and speculative encounters where soil becomes an ecological imaginary for attuning to the inextricable connectedness of the world. The project is grounded in the idea that if we are to care for soil we need first need to notice it. It is hoped insights from this research will help to nourish pedagogical terrains for children and teachers in troubled times