PlayPhrase.Me: A Multimedia Corpus for Foreign Language Education

Technological advancements have not only introduced new tools for language education but also tailored apps and resources for specific language skills. These include mobile apps (e.g., Drops: Language Learning Games for vocabulary), websites (e.g., SpanishDict for Spanish dictionary and grammar), and reference tools (e.g., Grammarly for writing assistance). One such resource is PlayPhrase.me, an online and mobile tool serving as a database of movie clips for language practice, particularly vocabulary. Despite the relative attention that similar tools (e.g., YouGlish and Voscreen) have received, only two studies have been conducted about the PlayPhrase.me website. Accordingly, there is a need for a review that outlines its general characteristics and pedagogical affordances. To this end, this review evaluated the website and revealed considerable potential for vocabulary, grammar, and pronunciation learning. Citing the possible pitfalls, such as short video durations, lack of filtering, and absence of evaluative and competitive means, the researcher offered recommendations for improvement. The review concludes with the researcher’s reflections as a teacher and urges further research to validate the findings

Kemik yapımını artıran uygulamalar: derleme

Kemik dokusu yaşam boyunca yeniden şekillenerek sürekli olarak kendini onarır ve yeniler. Kemiğin yeniden şekillenmesinde osteoprogenitör hücreler, osteoblastlar, osteoklastlar ve osteositler görev alır. Kemiğin yeniden şekillenme süreci, dolaşımdaki çeşitli hormonlar ve diğer lokal düzenleyici faktörler tarafından düzenlenir. Travma, kalıtsal eksiklikler ve patojeniteler kemik kaybına neden olabilmektedir. Klinik pratikte ise var olan kemik kaybını onarmak ya da rejenerasyonunu sağlamak oldukça zorlayıcı bir durumdur. “Doku mühendisliği” kavramının ortaya konulmasından bu yana son 25 yıldır kemik doku rejenerasyonu için stratejiler sürekli olarak gelişmektedir. Doku mühendisliğinde kemik yapımını desteklemek amacıyla çeşitli taşıyıcı iskele sistemleri, osteojenik özelliğe sahip mezenkimal kök hücreler ve osteoindüktif özellikte olan büyüme faktörleri, ilaçlar ve hormonlar araştırma konusu olmuştur. Nanoteknolojinin de rejeneratif mühendislik alanında uygulanmaya başlanması, taşıma sistemlerinin doku rejenerasyonu için gerekli olan biyouyumluluk, kimyasal ve mekanik özelliklerinin gelişmesini sağlarken aynı zamanda osteoindüktif materyallerin ve osteojenik hücrelerin salım konsantrasyonlarının kontrol edilebilmesini sağlamıştır. Bu derleme; kemik rejenerasyonunun artırılmasında osteoindüktif materyallerin güncel literatürler doğrultusunda mekanizmalarını, etkinliklerini ve klinik kullanımdaki yerlerini ortaya koymak ve ileride yapılabilecek çalışmalara ışık tutması amacıyla hazırlanmıştır.Bone tissue constantly reshapes and regenerates itself throughout life. Osteoprogenitor cells, osteoblasts, osteoclasts, and osteocytes play roles in bone reshaping. The process of bone remodeling is regulated by various hormones and local regulatory factors circulating in the body. Trauma, genetic deficiencies, and pathologies can lead to bone loss. In clinical practice, repairing existing bone loss or promoting regeneration is a challenging task. Over the past 25 years since the concept of "tissue engineering" emerged, strategies for bone tissue regeneration have been continuously evolving. Various scaffold systems that support bone formation, mesenchymal stem cells with osteogenic properties, and growth factors, drugs, and hormones with osteoinductive properties have been extensively researched in tissue engineering to enhance bone regeneration. The application of nanotechnology in regenerative engineering has further improved the biocompatibility, chemical, and mechanical properties of delivery systems required for tissue regeneration, while also allowing control over the release concentrations of osteoinductive materials and osteogenic cells. This review aims to shed light on the mechanisms, effectiveness, and clinical applications of osteoinductive materials in enhancing bone regeneration, based on current literature. The goal is to provide insights for future research and studies in this field

Three-dimensional Evaluation of the Anterior Maxillary Region in Skeletal Class II and Class III Patients in Terms of Fixation of Le Fort I Osteotomy Le Fort I Osteotomisinin Fiksasyonu Açısından İskeletsel Sınıf II ve Sınıf III Hastalarda Anterior Maksiller Bölgenin Üç Boyutlu Değerlendirilmesi

Background: This study aims to evaluate the volume and density of the anterior maxillary region in Class II and Class III patients using cone-beam computed tomography (CBCT) and to investigate whether there are differences between these two patient groups that could affect the stabilization of plates and screws. Methods: CBCT images of 48 patients (24 Class II and 24 Class III) were retrospectively examined. The volume of the maxillary anterior region (between the midline and the canine teeth), surface area and average density were calculated from the tomography images. Additionally, the distances of the maxillary canine, lateral and central teeth to the nasal fossa were measured. Results: No statistically significant differences were found between skeletal Class II and III patients in maxillary volume, surface area, density, or the vertical height of maxillary teeth to the nasal fossa floor (p>0.05). A statistically significant difference was observed between volume and surface area measurements on the right and left sides according to gender (p<0.05). Conclusion: There are no morphological differences between class II and class III patients that may affect the stabilization of the plates and screws used in the anterior region in Le Fort I osteotomy. However, preoperative evaluation of the distance between the anterior tooth roots and the nasal fossa and taking these distances into account when placing the screws is important in order to prevent damage to the tooth roots and to preserve tooth vitality