Data and code associated with the publication: Resourcefulness, robustness, and recovery: Tail use during climbing in rats

This repository contains the dataset and code used in the study of rats climbing up and onto a ledge. It contains sensor data, animal behavior data, experiment control, DeepLabCut trained models, and post-processed biomechanical data of 5 Long-Evans rats performing the climbing task described in the publication “Resourcefulness, robustness, and recovery: tail use during climbing in rats”

Data and code associated with the publication: The Effect of Global Skill Partnerships on Employment Status: Evidence from Morocco and Belgium

The dataset has the pre- and post-intervention data for the treatment and control groups for the Global Skill Partnership (GSP) in information and communications technology between Morocco and Belgium. The dataset is to be used for an impact evaluation of the GSP on employment status

Data and code associated with the publication: Phase contrast coronary blood velocity mapping with both high temporal and spatial resolution using triggered Golden Angle rotated Spiral k-t Sparse Parallel imaging (GASSP) with shifted binning

This work proposes a novel MRI method to measure blood flow and vessel cross-sectional area of the coronary arteries with a higher temporal and spatial resolution compared to currently available methods. The proposed methods includes both a new MRI acquisition method using a triggered golden angle (GA) scheme and a k-t sparse parallel imaging reconstruction algorithm that uses shifted binning that minimizes gaps in k-space to improve image quality. The method is tested in the right coronary artery (RCA) and the left anterior descending (LAD) artery of eight healthy subjects in an IRB approved study, and compared against current methods that have either high spatial or high temporal (but not both) resolutions

Data associated with the publication: General approach to achieving electrochemical aptamer-based sensor sensitivity of buffer in blood plasma

Electrochemical aptamer-based (E-AB) sensors enable the accurate measurement of target concentrations in complex matrices such as plasma or serum. However, to function effectively in these environments, the aptamers must resist nonspecific binding to proteins and other interferants. Many research literature and commercially available ("off-the-shelf") aptamers, originally selected without consideration for biofluid compatibility, are prone to such nonspecific interactions, which diminish sensor output and compromise sensitivity. To address this challenge and expand the utility of existing aptamer sequences, we present a tunable, generalizable method to restore the EC50 of E-AB sensors in plasma to levels comparable to those in buffer. We validate this approach using three therapeutically relevant small molecules: the antiretroviral emtricitabine (FTC), the antibiotic tobramycin, and the antimalarial hydroxyquinoline. Applying our method, we recovered EC50 values of 11 ± 3 µM for FTC (buffer: 10.4 ± 0.6 µM), 281 ± 91 µM for tobramycin (buffer: 190 ± 16 µM), and 1.1 ± 0.6 µM for hydroxyquinoline (buffer: 900 ± 95 µM). This strategy should enable the broader application of published small-molecule-binding aptamers for biofluid measurements, regardless of their original selection conditions

The Economist Intelligence Unit (EIU) CityData

EIU’s CityData contains pricing information on over 160 products and services in 140 cities worldwide, gathered from the EIU Worldwide Cost of Living Survey. More than 50,000 individual prices are collected by field correspondents in each survey. Prices are given for various stores: supermarkets, mid-priced stores, and higher-priced specialty outlets. Prices cover: National economic indicators; Food and drink; Household supplies; Personal care; Tobacco; Clothing; Utilities; Domestic help; Recreation; Transport; Office and residential rents; Schools, health and sports; Business trip costs; Salaries and disposable incomes. Prices correspond to the price the customer is charged, not recommended retail prices or manufacturers’ costs. Use CityData to support your market entry strategy, assess international pricing for a specific product(s), analyze historical pricing patterns for goods and services since 1990, compare the cost of doing business worldwide, and perform city-to-city pricing comparisons. EIU CityData provides the most complete picture of global price levels. More information is available at EIU CityData Information

Data and code associated with the publication: Rapid rebalancing of co-tuned ensemble activity in the auditory cortex

Sensory information is represented by small varying neuronal ensembles in sensory cortices. In the auditory cortex (AC) repeated presentations of the same sound activate differing ensembles indicating high trial-by trial variability in activity even though the sounds activate the same percept. Efficient processing of complex acoustic signals requires that these sparsely distributed neuronal ensembles actively interact in order to provide a constant percept. Thus, the differing ensembles might interact to process the incoming sound inputs. Here, we probe interactions within and across ensembles by combining in vivo 2-photon Ca2+ imaging and holographic optogenetic stimulation in awake mice to study how increased activity of single cells affects the cortical network. We stimulated a small number of neurons sharing the same frequency preference alongside the presentation of a target pure tone, further increasing their tone-evoked activity. We found that other non-stimulated co-tuned neurons decreased their tone-evoked activity when the frequency of the presented pure tone matched their tuning property, while non co-tuned neurons were unaffected. Activity decrease was greater for non-stimulated co-tuned neurons with higher frequency selectivity. Co-tuned and non co-tuned neurons were spatially intermingled. Our results show that co-tuned ensembles communicated and balanced their total activity across the larger network. The rebalanced network activity due to external stimulation remained constant. These effects suggest that co-tuned ensembles in AC interact and rapidly rebalance their activity to maintain encoding network dynamics, and that the rebalanced network is persistent

Data associated with the publication: Focus group discussions among Black women in Texas to inform a web-based intervention to increase HIV/STI self-testing, linkage to treatment, and linkage to PrEP

This data is from aim 1 of a NIMH R34 award. We conducted focus group discussions (FGDs) among 24 participants across 8 groups via Zoom. Participants included PrEP-eligible Black, cisgender women living in Texas. FGDs focused on components to inform a 5-session web-based intervention to increase HIV/STI self-testing, linkage to treatment, and linkage to PrEP. The FGD guide began with asking participants about their knowledge of HIV and STIs (i.e., transmission, prevention, treatment) and concern regarding contracting HIV or STIs. Next, we discussed facilitators and barriers to HIV/STI self-testing procedures (mental contrasting), and action plans (implementation intentions) to overcome barriers for each of the 5 intervention sessions: 1) using the HIV/STI self-test, 2) mailing the HIV/STI self-testing kit, 3) obtaining test results, 4) if applicable, obtaining treatment, and 5) linkage to PrEP. Lastly, we discussed potential names for the intervention and recruitment strategies

One Health POE Checklist for Transboundary Zoonotic Disease Preparedness

The One Health Point of Entry (POE) Checklist is a novel assessment tool developed to evaluate the multisectoral capacities of land border crossings and international airports in response to transboundary zoonotic disease (TZD) threats. Rooted in the One Health (OH) framework, which integrates human, animal, and environmental health sectors, the Checklist is designed to assess preparedness and operational readiness at POEs—critical junctures for trade, travel, and biosecurity. Developed through a collaborative process involving stakeholders from Iraq and Jordan, the Checklist is structured around the Prevent, Detect, Respond, and Evaluate framework. It draws from international guidance documents and includes 95–109 practitioner-focused questions depending on the POE type (land or air). These questions address topics ranging from personal protective equipment and zoonotic disease surveillance to cross-border communication and response planning. The checklist comes in two versions: the first for land border crossings, and the second developed international airports in mind. The Checklist offers a standardized, evidence-based approach for governments to assess and strengthen OH capacities at borders, complement existing global health security tools, and inform national-level decision-making for improved biosurveillance and emergency response

One Health Transboundary Assessment for Priority Zoonoses

The One Health Transboundary Assessment for Priority Zoonoses (OHTAPZ) tool is an assessment tool for cross-sectoral prioritization of transboundary zoonotic diseases (TZDs), and mapping of systems for One Health coordination at formal border crossings.  The tool uses a phased approach to bring together multisectoral stakeholders, create a consensus list of priority TZDs, identify existing processes for communication and coordination across and between sectors and levels, analyze strengths and weaknesses of existing operations, and recommend actions to address gaps in coordination from the local, subnational, national, and transboundary levels. OHTAPZ adds to the toolkit of modular, flexible, and easily adaptable approaches to One Health systems assessments that can support national, bilateral/regional capacity strengthening, regional epidemic preparedness, and compliance with international frameworks. See Center for Health Security: current projects. Provided is a copy of the manual and all appendices that are referenced in the manual, which can be downloaded individually in the "Files" tab section. To download the manual and all appendices as a single zip folder, choose “2025-10-OHTAPZ-JHRDR with Appendices.

Data and code associated with the publication: Patchy harmonic functional connectivity of the mouse auditory cortex

Analyzing the functional connectivity of the brain is an enormous challenge, as deciphering functional connectivity requires knowledge of functional responses and connections. One promising strategy is analyzing the spatial pattern of activity correlations across cell populations. In the primary auditory cortex (A1), cells respond to different sound features. On the large scale, there exists a tonotopic map, which is fractured at the small scale, raising the question of whether functional connections are spatially ordered or disordered. To test whether functional connectivity on a local and a global scale is also disordered, we first designed a robust statistical model to estimate parameters and test for the significance of the estimated correlation maps. We developed an inference method that allows efficient model fitting and statistical testing to project the correlation maps to 2D space. We then performed in vivo two-photon calcium imaging in Layer 2/3 of A1 with pure tones (PT) or a combination of two tones (TT; harmonically related or not). We found that the spatial patterns of signal (SC) correlations depend on the type of sound stimuli that were presented. The functional 2D maps of PT-driven SCs are more restricted to local neurons than TT signal correlations which showed more global textures. 2D SC patterns for harmonic stimuli showed spatially distinct relationships. TT SCs revealed spatially precise functional connectivity between harmonically related neurons. Thus, even though the frequency preference of neighboring neurons in A1 is functionally diverse, the functional connection pattern of these neurons is functionally precise and harmonically related