A comparative analysis of skin sparing optimization in head and neck cancer treatments

The study compares the skin-sparing optimization techniques used in Eclipse and RayStation TPS to inform guidelines and treatment protocols for VMAT head and neck cancer radiation therapy

Susceptibility to stress and nature exposure: unveiling the Integrative Model of Environmental Sensitivity

The objective of this program of research was to uncover potential mechanisms underpinning epidemiological evidence that groups in lower versus higher socioeconomic positions exhibit greater health benefits from nature exposure. One possible mechanism is described in the Integrative Model of Environmental Sensitivity: (susceptibility to stress) groups in lower socioeconomic positions are often exposed to more early-life stressors, which can induce a lifelong susceptibility to stress through various neurobiological pathways; (environmental sensitivity) susceptibility to stress, traditionally understood as heightened reactivity to stressors, could also encompass enhanced responsivity to health-protective exposures, inducing greater risks in adverse environments, but also greater benefits in protective environments. As the evidence for this framework expands, it could inform more targeted interventions that leverage individual differences in environmental sensitivity to promote health equity, ultimately providing more nuanced and socioeconomically attuned approaches to public health

Temperature changes (ΔT) in correlation with number of implant osteotomy preparations in human cadaver tibiae, comparing osseodensification (OD) burs in clockwise (CW) versus counterclockwise (CCW) mode

The purpose of the study was to evaluate the ΔT during the preparation of 360 implant osteotomies using osseodensification burs in clockwise and counterclockwise modes up to 60 times. One thousand (1000) RPM had the least effect in both modes and the 3.0 and 4.0 burs in the CCW mode drastically increased the temperature

The roles of technology, provider interaction, and therapeutic modality on the efficacy of iCBT to treat depression following the COVID-19 pandemic

A review of how technology, provider, interaction and therapeutic modality affect the effectiveness of iCBT in treating depression. Studies reviewed are conducted after the COVID-19 pandemic due to the expansion of teletherapy services during that time period

Understanding pupillometry in neuroscience critical care patients: a look at clinician usage, understanding, and perspective

This project performed a historical chart review on patients admitted to the neuroscience intensive care unit with documented pupillometry use, followed by a clinician survey informed by chart findings. Findings showed no consistent indications for pupillometry use. Utilization was highest amongst patients with hemorrhagic strokes, though practice varied. Survey results demonstrated that clinicians perceived pupillometry as a valuable tool, however providers often felt that the data was not regularly utilized in their clinical decision making. The absence of a standardized guideline or protocol contributes to variability in pupillometry use and limited understanding of its clinical significance. Additionally, pupillometry appeared to be utilized in response to clinical deterioration rather than as a part of routine monitoring. These results suggest a potential education gap around device usage and results interpretation

History of the Doernbecher Children's Hospital Guild

This paper was written by Burt Brown Barker who was the second president of the Doernbecher Children's Hospital Guild starting in 1943. He had previously served as both director and chairman. While his intended purpose for writing this detailed history of the Guild is not known, he provides a narrative of the creation of the Guild and an account of its good works. This includes a brief history of how Frank S. Doernbecher amassed his wealth, his decision to bequeath $200,000 to charity to benefit Oregonians, and how his children, Ada and Edward Doernbecher, acted as trustees and decided the money should be used to build a hospital for children. Barker describes the Guild's early organizational meetings in 1924 and lists many of the attendees who set about the task of raising the additional funds needed to open, run, and maintain Doernbecher Memorial Children's Hospital. There are excerpts of the Guild's constitution included in this report as well as rosters of early events, lists of early donations and how they were used, and notes of collaborations with many charitable groups. In one section, Barker proudly shares a report he requested from medical director Dr. Charles N. Holman, which includes three case studies that demonstrate Doernbecher's application of the latest medical concepts. The last few paragraphs provide the names of the dedicated personnel both at the Guild and at the hospital itself.Additionally, Barker explains that in 1923, prior to the Guild's formation, the Rotary Club had already decided to establish "The Rotary Crippled Children's Fund" for the treatment of sick and disabled children. He elaborates by describing a Rotary Club fundraiser that was an "old-fashioned minstrel show" which included racist imagery

Evaluation of metabolic activity diffusion imaging in resected human glioma

Representing the first study to employ Metabolic Activity Diffusion Imaging (MADI) within human brain cancer, this thesis serves as a demonstration of MADI's ability to probe cellular metabolism and cellular properties to evaluate tumor progression status in resected human gliomas. Three goals were pursued: (i) MADI's ability to differentiate normal tissue, tumor progression, and pseudoprogression, (ii) how MADI compares to a common metabolic activity imager FDG-PET, and (iii) identification of limitations and weaknesses in the current MADI approach

Assessment of junior faculty development in pediatrics

The assessment of junior faculty development at Oregon Health & Science University (OHSU) highlights the challenges new faculty face in accessing effective development resources within the Department of Pediatrics (DoP). Despite offering various programs aimed at enhancing leadership, teaching, research, and clinical skills, the absence of a centralized access system, coupled with barriers such as limited time, lack of program awareness, and scheduling conflicts, impedes engagement. Additionally, the lack of a systematic feedback loop makes it difficult to tailor these resources to faculty needs. To address these issues, the assessment recommends implementing structured feedback mechanisms, introducing a faculty development portal early in onboarding, creating a development roadmap, integrating growth discussions into annual reviews, and providing flexible participation options. By adopting these strategies, the department seeks to foster faculty growth, satisfaction, and retention, ultimately enhancing patient care and educational outcomes

Mindful analysis of informatics tools’ clinical utility in genomics: proposal for an expanded sociotechnical model framework

This work reviews the technical, clinical and ethical complexities related to use of genomic data to provide clinical informaticists a framework to evaluate the utility and risk of tools using genomic data

Longitudinal analysis of functional effort correction to assess lung damage after radiation therapy

This work examines the measured lung damages using different effort correction techniques. Functional effort correction method is examined with different parameters and marked over 3, 6, and 12 months post radiation therapy