埼玉医科大学看護学科紀要16巻1号 編集後記

departmental bulletin pape

新設科目「看護方法演習Ⅰ」のねらいと特徴 : 学生の施行する力,判断する力を育てる学習方法の導入

departmental bulletin pape

Asian population may have a lower incidence of hip osteonecrosis in childhood acute lymphoblastic leukemia

埼玉医科大学博士（医学）令和5年度thesi

Early changes in photopic negative response in eyes with glaucoma with and without choroidal detachment after filtration surgery

埼玉医科大学博士（医学）令和4年度thesi

Application of fluorescence in situ hybridization in distinguishing acral melanoma in situ from acral junctional nevus on the volar skin in Japanese patients

埼玉医科大学博士（医学）令和4年度thesi

Changes in in-hospital survival and long-term neurodevelopmental outcomes of extremely preterm infants: A retrospective study of a Japanese tertiary center

埼玉医科大学博士（医学）令和4年度thesi

The survival rate of patients with burns induced by explosions was significantly higher than that of common burn cases : A nationwide observational study using the Japan Trauma Data Bank

埼玉医科大学博士（医学）令和4年度thesi

トファシチニブによる潰瘍性大腸炎寛解導入療法における薬剤治療反応性バイオマーカーとしての血清IL2レセプターαの有用性の探索的検討

埼玉医科大学博士（医学）令和4年度thesi

Tumor budding and fibrotic focus-proposed grading system for tumor budding in invasive carcinoma no special type of the breast

埼玉医科大学博士（医学）令和4年度thesi

A neonate with early-onset group B Streptococcus (GBS) sepsis born from a mother who was negative in current maternal prenatal screening for GBS, but was positive in a previous pregnancy

Streptococcus agalactiaeに代表されるB群連鎖球菌(group B Streptococcus,以下GBS)は,新生児期から乳児期早期に感染すると髄膜炎や敗血症をきたすことが知られている.我々は,前回妊娠時にGBSスクリーニング陽性であったが,今回の妊娠中のスクリーニングでは陰性であったため,分娩時抗菌薬投与を施行しなかった母体から出生した正期産児が早発型GBS敗血症を発症した稀な症例を経験した.症例は在胎37週4日,体重2930gで出生した男児.在胎10週と36週に施行したGBSスクリーニングは陰性で,母体への分娩時抗菌薬投与は行われなかった.出生直後に感染徴候はなかったが,出生7時間後に呻吟と多呼吸が出現した.血液培養でGBSが同定され,早発型GBS敗血症と診断した.アンピシリンを10日間投与し軽快した.GBSスクリーニング陰性でもGBS感染症を発症しうることを念頭に置き,出生後の児の管理を行うことが大切である.また,本症例のような稀な症例を含めた早発型GBS敗血症を発症した新生児および母体のGBS検出状況など詳細なデータを集積することで,スクリーニング方法のさらなる改善に繋げていくことが重要であると考える.(著者抄録)Group B Streptococcus（GBS）is well-known to cause meningitis and sepsis in the neonatal period. Herein, we present a rare case of a full-term male neonate who developed early-onset sepsis by GBS delivered from a GBS screening negative mother. In last pregnancy, her GBS screening was positive, and she received antibiotics during her last delivery. Then, the child did not develop GBS infection. In this pregnancy, her GBS screening at the 10th and 36th week of gestation was negative, and antibiotics were not administered during this delivery. The child was born at 37 weeks of gestation and weighed 2930 g at birth. There were no signs of infection after birth, but he developed grunting and tachypnea at 7 hours after birth and was admitted to the neonatal intensive care unit. He was diagnosed with early-onset sepsis by GBS since GBS was identified in the blood culture. His symptoms were improved by the administration of ampicillin for 10 days and was discharged at 18 days of age without any developmental delay. It is important to manage a neonate after birth, keeping in mind that neonatal with GBS infection can develop even if the GBS screening is negative. The accumulation of the data of babies who are infected with early-onset GBS and GBS screening results of their mothers at pregnancy, including rare cases like ours, may provide better screening methods