International Journal of Medical Science Research and Practice (IJMSRP)
Not a member yet
82 research outputs found
Sort by
Decoding Sanjeevani: An Ethnobotanical, Pharmacological, and Historical Perspective on its Potential
Sanjeevani, the revered medicinal plant of great heritage in Indian mythology and traditional medicine, has fascinated herbalists and scientists alike for many centuries. In spite of much controversy regarding botanical classification, several plant species including Selaginella bryopteris and Cressa cretica have been nominated as likely possibilities. The current study investigates Sanjeevani from ethnobotanical, pharmacological, and historical perspectives in order to determine its therapeutic prospect.
Ethnobotanical research has shown that a number of plants connected with Sanjeevani are used in Ayurveda and folk medicine for their healing, adaptogenic, and wound-healing action. Pharmacological studies have shown that these plants have bioactive phytochemicals with antioxidant, anti-inflammatory, and neuroprotective activity, which may justify their traditional use for their potential to heal. There is limited scientific evidence, and further clinical trials are required.
Sanjeevani has always been considered a miraculous drug, and most noticeably is mentioned in the Ramayana for reviving unconscious warriors. The article tries to analyze ancient texts, myths, and modern perceptions in an effort to close the gap between legend and science.
Employing an interdisciplinary strategy, the research in this study hopes to enlighten on the medicinal importance of Sanjeevani by highlighting serious pharmacological evaluations, conservation practices, and merging local knowledge with modern medicine. Through the translation of Sanjeevani’s ancient heritage, this research adds to the understanding of medicinal plants in whole-healing medication and what they can do in modern medicine
The Impact of Medical Jargon on the Daily Communication of Medical Science Students
This study seeks to analyze the impact of medical jargon on the daily communication practices of medical science students. It recognizes medical jargon as the main aspect of both identity and communication within the medical field. By delving into the routine use of specialized terminology, the research aims to uncover how this linguistic practice shapes the effectiveness of communication among students. The study adopts a qualitative methodology, employing interviews with students and scrutinizing the content of their discussions to gauge their perceptions and sentiments regarding the utilization of medical jargon. Through meticulous data analysis, the study intends to elucidate the experiences of students and the extent to which the use of jargon influences their everyday communication. This study aims to shed light on how medical jargon shapes communication among medical students, both as a tool for professional identity and as a potential barrier to clear conversations. By exploring students’ everyday use of specialized terminology, the research uncovers the ways jargon influences their interactions. Beyond understanding this dynamic, the study offers practical insights that could help refine communication training in medical education. Unlike previous research, which often focuses on jargon in doctor-patient settings, this study highlights its impact within student interactions—an area that has received little attention. These findings could inspire improvements in medical training programs, helping future healthcare professionals communicate more effectively while maintaining the precision of their field
Assessment of the Functional State of the Cardiovascular System in Patients with Diabetes and Hypertension Who Have Recovered from COVID-19
Patients with diabetes and hypertension who recover from COVID-19 face elevated cardiovascular risks, necessitating a comprehensive evaluation of their cardiovascular functional state. This review synthesizes current evidence on the functional changes in the cardiovascular system post-SARS-CoV-2 infection among this high-risk group, focusing on myocardial injury, endothelial dysfunction, and persistent symptoms. SARS-CoV-2 exacerbates pre-existing vulnerabilities through direct viral invasion, systemic inflammation, and hypercoagulability, leading to increased incidences of myocardial fibrosis, left ventricular dysfunction, and arrhythmias. Diagnostic tools such as echocardiography, cardiac MRI, and biomarkers like troponin and NT-proBNP reveal these alterations, with global data indicating a significant public health challenge—over 422 million people with diabetes and 1.28 billion with hypertension are affected. This study examines pathophysiological mechanisms, clinical manifestations, diagnostic approaches, and long-term outcomes, highlighting the need for tailored management strategies. While evidence underscores heightened morbidity, gaps persist in individualized treatment and long-term follow-up protocols. These findings aim to inform clinicians in optimizing care, reducing complications, and improving prognosis for this vulnerable population, with implications for global health systems addressing post-COVID sequelae
Treacher-Collins syndrome
INTRODUCTION- Treacher Collins syndrome (TCS) is a rare syndrome inherited as autosomal dominant. The affected children may vary in severity ranging from minimal features as slanting of palpebral fissures to major features of craniofacial development such as hypertelorism, micrognathia, maxillary hypoplasia, high arched palate, conductive hearing loss, external ear abnormalities and narrow nostrils. We report a case of Treacher Collins syndrome with term gestation with polyhydramnios and fetus with micrognathia on ultrasound examination with previous two babies and father having the same disorder.
Case Report- A 30year old ,unbooked G3 P2 L1D1, postcesaerean pregnancy, term gestation with polyhydramnios with breech presentation with features of TCS admitted for institutional delivery at Government General Hospital, Kakinada, Andhra Pradesh, India. Her scan on admission revealed single fetus in breech presentation with micrognathia and AFI 25cm. she delivered a live male baby weighing 2.2kg with features of TCS through ceserean section and inspite of airway support the baby died on first postnatal day.
Conclusion- This case report confirms the need to identify the antenatal women with physical malformations and early ultrasound scan in women with previous H/O anomalous children, and polyhydramnios so that termination can be planned early
Comparing Quality of Life Post Myopic Astigmatic Refractive Surgeries: FS-LASIK vs ICL
Background: This study aims to compare the postoperative outcomes of femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and implantable collamer lens (ICL) implantation in improving visual acuity, contrast sensitivity, and quality of life (QoL) in patients with myopia or myopic astigmatism. Methods: A prospective, interventional, and observational study was conducted at a tertiary eye care center in Surat, India, involving 120 eyes of 60 patients (30 in each group). Preoperative and postoperative assessments included demographic data, visual acuity measurements (both uncorrected and best corrected), contrast sensitivity, and QoL evaluations using the Quality-of-Life Impact of Refractive Correction (QIRC) questionnaire. Results: Both FS-LASIK and ICL significantly improved visual acuity postoperatively, with average uncorrected visual acuity (UCVA) improving from 1.4 ± 0.22 logMAR to 0.1 ± 0.13 logMAR in both groups. The mean spherical equivalent reduced significantly, with FS-LASIK achieving -0.52 ± 0.32 D and ICL achieving -0.87 ± 0.40 D after surgery. Contrast sensitivity also improved in both groups, although no significant differences were observed between them. QoL assessments indicated that both groups experienced significant postoperative improvements, with the ICL group reporting slightly higher QIRC scores (59.34 ± 9.477) compared to FS-LASIK (56.39 ± 8.42). Conclusion: Both FS-LASIK and ICL are effective surgical options for correcting myopia, resulting in substantial improvements in visual acuity, contrast sensitivity, and QoL. While both procedures significantly enhance patient satisfaction and visual independence, the ICL group exhibited marginally superior QoL outcomes. Further long-term studies are warranted to evaluate the durability of these benefits and to better understand the influence of patient-specific factors on treatment outcomes.
 
Prevalence and Impact of Non-Strabismic Binocular Vision Disorders among College Students in Surat District, Gujarat: A Cross-Sectional Study
Objective: This study aimed to investigate the prevalence of Non-Strabismic Binocular Vision Disorders (NSBVD), including Convergence Insufficiency (CI) and Accommodative Insufficiency (AI), among college students in Surat, Gujarat, and to explore correlations with screen time and academic demands. Methods: A cross-sectional study was conducted with 300 college students aged 18–25 years. Participants underwent binocular vision assessments, including Near Point of Convergence (NPC), Near Point of Accommodation (NPA), and fusional vergence testing. Data were analyzed using chi-square tests and descriptive statistics to determine the prevalence of NSBVD and its associations with screen time. Results: The overall prevalence of NSBVD was 30% (95% CI: 25.1% - 34.9%). Convergence Insufficiency was the most common disorder, affecting 18% (95% CI: 13.8% - 22.2%) of students, followed by Accommodative Insufficiency (8%, 95% CI: 5.0% - 11.0%) and Accommodative Excess (4%, 95% CI: 2.0% - 6.0%). High screen time (>6 hours/day) was strongly associated with increased NSBVD prevalence, with 40% of participants in this group exhibiting symptoms of NSBVD, particularly CI (22%). No significant age or gender differences in NSBVD prevalence were observed. Conclusion: The study identifies a high prevalence of NSBVD among college students, especially those with prolonged screen time. These findings highlight the need for routine visual health screenings, ergonomic interventions, and targeted vision therapy to alleviate visual strain and support academic performance. Prolonged screen exposure and academic pressures should be considered critical factors in the management of NSBVD in young adults.
 
Unravelling the Patterns of Antinuclear Antibodies (ANA) Indirect Immunofluorescence Assay (IFA): Insights and Implications
The Antinuclear Antibodies (ANA) Indirect Immunofluorescence Assay (IFA) has long been a cornerstone for diagnosis and management of autoimmune diseases. This review aims to elucidate the diverse patterns observed in ANA IFA, exploring their clinical significance, diagnostic utility, and evolving implications in autoimmune diagnostics. We delve into the intricacies of interpreting ANA IFA patterns, emphasizing their correlation with specific autoimmune diseases and highlighting recent advancements in pattern recognition technologies. Furthermore, we discuss challenges, limitations, and future directions in ANA IFA interpretation, paving the way for enhanced precision and efficacy in autoimmune disease diagnosis.
 
Bisalbuminemia: Insights into its Clinical Manifestations, Diagnostic Complexities, and Relevance in Modern Medicine
Bisalbuminemia, also known as alloalbuminemia, is a rare hematologic disorder characterized by the presence of two distinct serum albumin fractions in the blood. This condition is typically benign and asymptomatic, but its discovery can be puzzling for clinicians due to its rarity and often incidental nature. The occurrence of bisalbuminemia can be hereditary or acquired, with the hereditary form being passed down in an autosomal dominant fashion, while the acquired form is linked to liver disease, kidney disease, or drug exposure. The condition is most commonly identified during routine serum protein electrophoresis (SPE) testing, when an unusual albumin pattern is observed. In this report, we present a case of a patient diagnosed with bisalbuminemia. We discuss the clinical presentation, diagnostic challenges, and management strategies, emphasizing the importance of considering rare hematologic conditions in patients presenting with unexplained hypoalbuminemia and abnormal serum protein electrophoresis results. This case underscores the need for awareness of such conditions among clinicians and laboratory personnel to avoid unnecessary testing and misdiagnoses.
 
Semaglutide and Obesity: Real-World Clinical Applications and Outcomes
Obesity, a chronic and complex disease, is projected to have a prevalence of 49% by 2030 and is linked to various comorbidities, including type 2 diabetes, hypertension, dyslipidemia, stroke, coronary heart disease, and cancers, resulting in a substantial economic burden. Effective weight management is crucial to reduce morbidity and mortality. Semaglutide, initially developed as a GLP-1 receptor agonist for treating type 2 diabetes, is now being explored for its potential in addressing obesity. Its utilization is expanding to chronic weight management as it mimics the effects of GLP-1, regulating blood sugar levels and appetite. The FDA approved the use of a 2.4 mg injection of semaglutide once weekly for chronic weight management. Semaglutide proves efficacy for weight loss in obesity, endorsed by STEP trial findings and real-world data, with safety akin to GLP-1RA class, promoting long-term adherence. Its notable effects on albuminuria, HbA1c, heart failure, and quality of life herald a transformative paradigm in obesity and associated comorbidity management. Through a review of existing literature and clinical studies, this article provides a nuanced overview of the diverse real-world scenarios where semaglutide has been applied, elucidating its impact on weight management and associated health outcomes.
 
Exploring the Impact of Mind-Healing Techniques on Mitral Valve Area Improvement: A Clinical Case Study
This clinical case study investigates the potential influence of mind-healing techniques on the improvement of mitral valve area in a patient diagnosed with mitral stenosis. The study explores the integration of mindfulness-based interventions alongside conventional medical treatment and assesses the clinical outcomes, focusing on echocardiographic measures of mitral valve area