都市デザイン系研究発表題目一覧

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模擬運転テストの危険予測場面でみられる視線動作と手掌部発汗・脳血流反応

Article発汗学.24(1):16-18(2017)journal articl

次代の地域ブランド構築と大学の役割

地域ブランドの浸透は,ランキングや認定制度など新たな価値基準を生み出した.それに対応するため各ブランドは,グローバル化への対応,エビデンスの強化,ブランド維持のための産学官民の連携体制構築など新たな取り組みを求められるようになっている.これら新たな社会的価値への対応はブランド提供者の責務である.しかし,地域ブランドの送り手は,小さな組織の集合体であることが多く,対応が困難な場合も多い.地域の一員として,専門機関として,ミッションとして,地域ブランド構築に関し大学への期待が寄せられている.また,大学も地域ブランド構築への参加を好機と捉えて,研究や教育に活用することが重要となっている.Article産学連携学.13(1):39-47(2016)journal articl

Dysfunction of Protein Quality control in Parkinsonism-Dementia complex of Guam

Guam parkinsonism-dementia complex (G-PDC) is an enigmatic neurodegenerative disease that is endemic to the Pacific island of Guam. G-PDC patients are clinically characterized by progressive cognitive impairment and parkinsonism. Neuropathologically, G-PDC is characterized by abundant neurofibrillary tangles, which are composed of hyperphosphorylated tau, marked deposition of 43-kDa TAR DNA-binding protein, and neuronal loss. Although both genetic and environmental factors have been implicated, the etiology and pathogenesis of G-PDC remain unknown. Recent neuropathological studies have provided new clues about the pathomechanisms involved in G-PDC. For example, deposition of abnormal components of the protein quality control system in brains of G-PDC patients indicates a role for proteostasis imbalance in the disease. This opens up promising avenues for new research on G-PDC and could have important implications for the study of other neurodegenerative disorders.ArticleFRONTIERS IN NEUROLOGY.9:173(2018)journal articl

（資料）本多静六著『隠れたる木曽の風景と利用策』（大正二年）の現代語訳

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Fabrication of high thermal conductivity Cu/diamond composites at ambient temperature and pressure

High thermal conductivity Cu/diamond composites were produced at ambient temperature and pressure using an electrodeposition technique, employing various diamond particle sizes in the range of 10 to 230 mu m. The microstructures of the resulting composites were analyzed by scanning electron microscopy and their thermal conductivities were assessed using a Xenon flash instrument. The theoretical thermal conductivities of these materials were calculated based on the Hasselman-Johnson equation and compared with the experimentally determined values. The Cu/diamond composites produced in this work were found to exhibit compact textures without any gaps between the Cu matrix and the diamond particles, and the experimental thermal conductivities were in good agreement with the theoretical values. The specimen containing 61 vol.% of 230 mu m diameter diamond particles had the highest conductivity of 662 W K-1 m(-1), which is 1.6 times that of pure Cu (ca. 400 W K-1 m(-1)). (C) 2019 Author(s).ArticleAIP ADVANCES. 9(8):085309 (2019)journal articl

Cellular Responses of Human Lymphatic Endothelial Cells to Carbon Nanomaterials

One of the greatest challenges to overcome in the pursuit of the medical application of carbon nanomaterials (CNMs) is safety. Particularly, when considering the use of CNMs in drug delivery systems (DDSs), evaluation of safety at the accumulation site is an essential step. In this study, we evaluated the toxicity of carbon nanohorns (CNHs), which are potential DDSs, using human lymph node endothelial cells that have been reported to accumulate CNMs, as a comparison to fibrous, multi-walled carbon nanotubes (MWCNTs) and particulate carbon black (CB). The effect of different surface characteristics was also evaluated using two types of CNHs (untreated and oxidized). In the fibrous MWCNT, cell growth suppression, as well as expression of inflammatory cytokine genes was observed, as in previous reports. In contrast, no significant toxicity was observed for particulate CB and CNHs, which was different from the report of CB cytotoxicity in vascular endothelial cells. These results show that (1) lymph endothelial cells need to be tested separately from other endothelial cells for safety evaluation of nanomaterials, and (2) the potential of CNHs as DDSs.ArticleNANOMATERIALS. 10(7):1374 (2020)journal articl

Stellar Stratifications on Classifying Spaces

Book chapterAlgebraic Topology and Related Topics: 287-313(2019)boo

目次

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精神科看護師のコンピテンシーと職場ストレッサーとの関係

【目的】精神科看護師のコンピテンシーと精神科看護師の職場ストレッサーの関連を明らかにする。【方法】A県内の精神科病棟看護師318名に精神科看護師のコンピテンシーおよび職場ストレッサーについて自記式質問紙調査を実施した。分析は、146名分の回答の記述統計、属性ごとの得点、精神科看護師のコンピテンシーを問う項目の得点を基に3群に分けた職場ストレッサー尺度得点の群間比較である。【結果】精神科看護師のコンピテンシーは、その構成因子である「多職種との協働による総合的なサービス提供」の得点が高く、「エビデンスに基づく治療と危機への介入」は低かった。また、「ライフヒストリー」、「情緒的反応への対応」、「情報提供と支援」の高得点群は、中・低得点群より職場ストレッサー得点が低かった。【考察】精神科看護師は、コンピテンシーの得点が低かった「ライフヒストリー」、「情緒的反応への対応」、「情報提供と支援」に関連する知識・スキルの学習、それに伴う動因や自己イメージの変容に取り組むことがコンピテンシーの発揮と職場ストレッサーの低減に重要である。［Objective］To clarify the relationships between nursesʼ competencies and workplace stressors on psychiatric wards. ［Methods］A questionnaire survey was conducted involving 318 nurses working on psychiatric wards in a single prefecture to examine scores from self-administered questionnaire survey of psychiatric nursing competency and workplace stressor scales. Responses from 146 nurses were analyzed by calculating descriptive statistics, comparing scores based on attributes, and comparing workplace stressor scale scores among 3 groups based on the total psychiatric nursing competency scale. ［Results］On comparing factors representing psychiatric nursesʼ competencies, 〈comprehensive services for profession〉 achieved a signifi cantly higher score, whereas the score for 〈evidence-based treatment and crisis intervention〉 was markedly lower. Furthermore, nurses with high scores for 〈life histories〉, 〈emotional response management〉, and 〈information provision and support〉 showed lower workplace stressor scale scores than those with low/intermediate scores for these factors. ［Conclusions］It may be eff ective for psychiatric nurses to acquire knowledge/skills related to 〈life histories〉, 〈emotional response management〉, and 〈information provision and support〉 representing psychiatric nursesʼ competencies, and address their motives and self-images for such acquisition, in order to develop higher-level competencies with reduced workplace stressors.departmental bulletin pape