47044 research outputs found
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Tom Deluca -Trevarthan [Neg # 33A]
Roll of B+W Film scanned, Images of Hypnotist/Comedian Tom Deluca hypnotizing UNF students on stage; Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/2429/thumbnail.jp
Interactions between lipopolysaccharide and capsule retention in Klebsiella pneumoniae and the resultant effects on macrophages
Klebsiella pneumoniae is the third most common cause of nosocomial infections in the United States. The capsular polysaccharides (CPS) are virulence factors allowing K. pneumoniae to evade host immune systems. The current model of capsule structure indicates that CPS fibrils interact with the external O-antigen of lipopolysaccharide molecules to enhance retention to the bacterial outer membrane. These interactions may influence pathogenicity in clinically relevant strains. This study characterized alterations to LPS and CPS structure, the impact of these changes on capsule retention, membrane permeability, biofilm formation, and macrophage interactions. LPS and CPS were quantified and visualized in four strains of K. pneumoniae: lab strain ATCC 43816, O-antigen knockout ΔwbbO, capsule knockout ΔwcaJ, and lab-evolved cephalothin resistant strain 14T which harbors multiple mutations, including in the capsule synthesis gene wcaJ. ΔwbbO exhibited significantly less CPS compared to 43816 despite exhibiting similar quantities of LPS core structures to 43816. Visualization of LPS from each strain via SDS-PAGE confirmed the absence of O-antigen associated LPS in the ΔwbbO strain. These results corroborate the suggested model that capsule retention is, in part, associated with the LPS O-antigen in K. pneumoniae. Strain 14T showed significantly increased LPS content compared to the three other strains, but similar CPS content to ΔwcaJ. Membrane permeability decreased only in ΔwbbO. Biofilm formation was significantly increased in both ΔwcaJ and 14T. This study also explored alterations to macrophage viability, bactericidal activity, and phagocytosis of bacteria, with variations in CPS and LPS. Infection with ΔwcaJ and 14T resulted in higher phagocytosis and increased bactericidal activity but similar drop in macrophage viability to 43816. Infection with ΔwbbO resulted in similar phagocytosis to 43816 but reduced bactericidal activity and increased macrophage viability. These results suggest that capsule retention is complex, associated with more than LPS, and may influence virulence and outcomes of infection
Portrait of Harriet Cook LeMaster
This oil painting depicts a woman seated on the far left of a sofa, next to a lamp.https://digitalcommons.unf.edu/campus_art/1805/thumbnail.jp
The Life and Works of Rev. James S. Todd, D. D.
Program: Reverend James S. Todd, prominent religious leader of Florida. Note: Eartha White listed on page 7-8 as a dynamic member of the Negro Health Committee of which Rev. Todd served as the first President. Undated
UNF VS Flagler [Women] Trevarthan Roll 2 [Neg # 4A]
Roll of B+W Film scanned, UNF Women\u27s Basketball Trevarthan, Unidentified basketball players, Roll 2; Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1700/thumbnail.jp
Antisocial behavior among students in Florida school districts and their associated disciplinary approaches: A cross-lagged panel design
Research suggests that antisocial behavior is a major problem for all those involved in school environments. Additionally, despite the prevalence of using harsher punishments in response to such behavior, these practices may present more negative rather than positive consequences. The aim of the current study was to explore antisocial behavior in schools and the disciplinary approaches used in response to such behavior. Using disciplinary data reported for public schools in 67 districts of the state of Florida, the prevalence of antisocial behavior incidents was compared to the prevalence of other, drug-related incidents. A cross-lagged panel model determined whether a preference for exclusionary practices or rates of antisocial behavior incidents in previous years was a stronger predictor of antisocial behavior in following years. We found no relationship between the disproportionate use of exclusionary practices and the increased risk of severe antisocial behavior in subsequent years. In contrast, we found that the risk of severe antisocial behavior within schools often predicted less general use of exclusionary practices in subsequent years, rather than the inverse. Determining the relationship between antisocial behavior and the disciplinary practices used to address these behaviors can have important implications for school staff, helping to create safe, productive learning environments
Career Adventure [Neg # 37A]
Roll of B+W Film scanned; Images of Zoo Animals; Financial Planning Meeting; Headshots; Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1810/thumbnail.jp
Career Adventure [Neg # 6A]
Roll of B+W Film scanned; Images of Zoo Animals; Financial Planning Meeting; Headshots; Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1820/thumbnail.jp
Brush Fire/Candidates-Trevarthan [Neg # 31A]
Roll of B+W Film scanned; Brush Fire/Candidates; Unidentified tennis player; Headshots-Trevarthan; Date: undatedhttps://digitalcommons.unf.edu/spinnaker-images/1777/thumbnail.jp
UNF VS Flagler [Women] Trevarthan [Neg # 42A]
Roll of B+W Film scanned, UNF Women\u27s Basketball Trevarthan, Unidentified basketball players, Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1675/thumbnail.jp