Outcomes of Adenomyosis in Pregnancy

EDITORIA

From Cognitive Elitism to Cognitive Emotional Elitism: Loopholes Need Bridging with “Serene Brain Potentials”

The paper critically examines cognitive elitism, the belief that intellectual ability alone defines merit and leadership.Originating from controversial theories, cognitive elitism marginalizes emotional intelligence, morality, and social values,fostering inequality and social fragmentation. The authors argue that overemphasis on intelligence and academic successundermines empathy, ethics, and inclusivity. To address these issues, the article proposes a transformative concept: cognitiveemotional elitism, incorporating the ME3V model—Morality, Ethics, Empathy, Emotional intelligence, and Values. Thisredefined elitism seeks to balance intellect with humanity, promoting social cohesion, equity, and pluralism. The paper callsfor inclusive recognition of diverse cognitive strengths beyond traditional elitist frameworks

Insulin Stewardship in Times of Change

Brief Communicatio

Early Diagnosis of Secondary Hypertension in South Asia: A Public Health Imperative

mortality. While essential hypertension forms the bulk of cases, a substantial proportion- estimated around 10%- is attributableto secondary hypertension. These cases are often underdiagnosed, particularly in resource-limited settings. Failure to detectand treat secondary causes early leads to resistant hypertension, target organ damage, and increased health care costs. Thisarticle emphasizes the critical need for awareness, early diagnosis, and structured management of secondary hypertension inSouth Asia. We propose policy-level interventions and region-specific solutions to address the systemic gaps and recommendan integrated, multidisciplinary approach.&nbsp

What is the Diagnosis?

Picture Qui

Unveiling the Eschar: A Mite’s Mark in Scrub Typhus

Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi, a Gram-negative intracellular organism transmittedby Leptotrombidium mites, with wild rats serving as natural reservoirs. The disease is more common in the TsutsugamushiTriangle, often afflicting travelers and creating diagnostic challenges in clinical practice. We present the case of a diabeticpatient who acquired the infection while visiting an agricultural farm. Our discussion covers clinical manifestations,diagnostic markers and treatment modalities, emphasizing the significance of early recognition and the benefits of prompttreatment. The importance of searching for an eschar, a key physical sign, is underscored and potential serious outcomesare discussed. Recent advances and preventive measures are also highlighted. This synthesis of research and clinical insightsaims to enhance global awareness, prompt diagnosis, and effective management of scrub typhus

Pre-eclampsia and Thrombosis Risk

EDITORIA

An Unusual Presentation of Splenic Rupture in a Hemodialysis Patient

Splenic rupture, although rare in dialysis patients, can be life-threatening. In this case, a 45-year-old man with kidney failureon hemodialysis experienced sudden and severe abdominal pain in the left flank, without any history of trauma. He displayedsymptoms of hypovolemic shock, characterized by pallor, hypotension, and tachycardia. Additionally, he had abdominaldistension and tenderness. An abdominal CT scan revealed a splenic hematoma and intra-abdominal hemorrhage. Thepatient required a splenectomy to address the ongoing bleeding, but unfortunately, he succumbed to post-splenectomy sepsis2 weeks later

Oxiconazole: A Comprehensive Review on its Role in Superficial Fungal Infections

Oxiconazole is a topical antifungal medicine that belongs to the imidazole group. It is mainly used to treat superficial fungalinfections of the skin. It works well against different types of fungi, including dermatophytes (which cause skin infections),Candida species (a type of yeast), and some Gram-positive bacteria. Health care professionals commonly use oxiconazole totreat conditions like athlete’s foot (tinea pedis), ringworm of the body (tinea corporis), and tinea versicolor (a skin infectionthat causes discolored patches). Oxiconazole mainly stops fungi from growing (fungistatic effect), but at higher doses, itmay kill them directly (fungicidal effect). It works by blocking the production of ergosterol, an essential part of the fungalcell membrane. Without ergosterol, the membrane becomes weak and leaky, disrupting normal cell function. This reviewhighlights oxiconazole’s mode of action, range of antifungal activity, clinical uses, resistance patterns, and safety. It showswhy oxiconazole remains a valuable option in treating skin fungal infections

Iron Deficiency in Heart Failure: Unveiling the Hidden Culprit

Iron deficiency (ID) is a frequent comorbidity in patients with heart failure (HF). Coexistent HF and ID make the issuesmore challenging to diagnose and treat. Iron deficiency exacerbates clinical symptoms, impairs quality of life and increasesthe risk of recurrent hospitalization for HF. Conversely, a proinflammatory state and altered gut kinetic in HF may resultin absolute or functional ID, which conventional laboratory makers may not diagnose and differentiate accurately. Noveldiagnostic markers like soluble transferrin receptor (sTfR), reticulocyte hemoglobin concentration, red blood cell distributionwidth, sTfR: log (ferritin) ratio and serum hepcidin levels may help to diagnose ID more accurately in the setting of HF. Theintravenous (IV) iron formulation has shown promising results in improving the functional class and reducing recurrenthospitalization in patients with HF and ID. Futuristic therapies like nanosized iron preparations, hepcidin inhibitors andhepcidin antagonists may help manage ID more efficiently and conveniently in HF. This manuscript explores the relationshipbetween ID and HF. It also provides the latest information related to the diagnosis and treatment of ID in HF patients