Main clinical findings on the use of the zygomatic implant for compromised maxillary bone: a systematic review

Introduction: In the dental implant scenario, the graft to treat severely reabsorbed jaws is currently the gold standard procedure. Still, there are flaws in this procedure until 30.0 % are reported in the literature. Zygomatic implants have shown, in many cases, improved clinical outcomes compared to bone grafts and represent an essential alternative for compromised maxillary bone. Objective: It was analyzed the main literary findings on the use of the zygomatic implant as a necessary alternative for a dental implant. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from November 2024 to January 2025 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: 122 articles were found, 36 articles were evaluated in full and 34 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 24 studies with a high risk of bias and 38 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=83.7%>50%. It was concluded that the zygomatic implant is revolutionizing the procedure of implants in the posterior atrophic maxilla, eliminating the complications of bone augmentation and sinus elevation with delayed cicatrization. Zygomatic implants have, in many cases, shown better clinical results compared to bone grafts and represent a possible gold standard for dental implants

Major clinical outcomes of parendodontic surgery in patients with chronic non-communicable diseases: a systematic review

Introduction: In the context of chronic diseases and the challenges of endodontic surgery, there are some cases where, even after the correct use of endodontic resources, treatment fails, and the endodontist's first option is to perform retreatment. Objective: It was to develop a systematic review to list the main approaches and clinical challenges of endodontic surgery. Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from November to December 2024 in Scopus, Embase, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 230 articles were found, and 37 articles were evaluated in full and 26 were included and developed in this systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 33 studies with a high risk of bias and 53 studies that did not meet GRADE and AMSTAR-2. It was concluded that periodontal surgery is a viable, safe, and effective alternative for patients with chronic diseases. Proper planning, where indications are taken into account, is directly linked to the success rate of clinical cases. Apicoectomy combined with apical curettage significantly improves the prognosis of the case. Mineral Trioxide Aggregate is the material most often described as having the highest positivity for retrofilling. The best way to perform a retroperitoneal preparation is with the aid of ultrasound. The laser is a technological advance in the decontamination of the apical region, and the microscope is a magnificent aid in visualizing the operated area, increasing the rate of surgical success. Through a correct diagnosis and the technique chosen to perform the surgical treatment, it is possible to have a successful surgery and an excellent prognosis. Thus, the success rates of endodontic surgeries depend on the indication of the surgical modality, retro-obturator materials, previous quality of the root canal filling, treatment of the surgical pocket, execution of the surgical technique, and periodontal conditions

Major clinical outcomes of pulsed-dye laser treatment for vascular melasma: a concise systematic review

Introduction: In recent years, dermatology has advanced in its treatments with the introduction of laser technology. In particular, the pulsed-dye laser (PDL) has a wavelength of approximately 595 nm and is used to destroy hemoglobin in blood vessels. Melasma is an important target for PDL treatment. Objective: It was carried out a concise systematic review to highlight the major clinical studies on the use of pulsed-dye lasers in the treatment of melasma. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from February to April 2025 in the Scopus, Embase, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: 87 articles were found, 19 articles were evaluated in full and 09 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 15 studies with a high risk of bias and 27 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=87.7%>50%. It was concluded that the combination of pulsed dye laser with low-fluence Q-switched Nd: YAG laser can be considered a safe and effective treatment for patients with melasma who present visibly dilated capillaries on dermoscopy. Both pulsed dye laser and intense pulsed light were effective and safe treatment modalities for the lightening of melasma. Furthermore, melasma lesions that present subtle or subclinical telangiectatic erythema can be improved by combining targeted vascular laser therapy and low-level fractional diode laser therapy. A parallel improvement in telangiectatic erythema suggests a relationship between the underlying vasculature and hyperpigmentation

Major considerations and findings of clinical studies on zygomatic implant placement in older patients with severe maxillary atrophy: a systematic review

Introduction: Zygomatic implant (ZI) rehabilitation of edentulous patients with maxillary atrophy is an approach that has been used with well-standardized procedures and considerable survival. Objective: The aim was to address and describe the main considerations and findings of clinical studies on the placement of zygomatic implants in elderly patients with severe maxillary atrophy. Methods: The present study followed a concise systematic review model (PRISMA rules). The search was carried out in the PubMed, Embase, Ovid, Cochrane Library, Web of Science, and Scopus databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 116 articles were found. In total, 41 articles were fully evaluated and 25 were included and evaluated in this study. Of the initial total of articles, 28 articles were excluded because they did not meet the GRADE and AMSTAR-2 classification, and 12 were excluded because they presented a risk of bias that could compromise the credibility of the studies. The symmetric funnel plot does not suggest a risk of bias. According to the GRADE instrument, most studies presented homogeneity in their results, with X2=92.1%>50%. It was concluded that the use of zygomatic implants is an alternative procedure, making implant rehabilitation of extensively atrophic maxillas possible when conventional procedures are not possible. Several anatomical and procedural factors, such as sinus conformation and sinus mucosa thickness, may influence the overall success of zygomatic implant rehabilitation and predispose to a higher occurrence of complications. Furthermore, dynamic navigation technology had better predictability in terms of precision and accuracy

Major clinical findings on the types of impressions used in implant-supported prostheses: a systematic review

Introduction: The key to obtaining perfect prostheses depends on the passive fit between its connector and the implant itself. The compromised fit between the contact surfaces of implant-supported prostheses creates uncontrolled stresses in the components and peri-implant tissues, evoking biological and mechanical complications. Objective: It was to review the scientific literature on the types of impression used in implant prostheses. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from July to August 2024 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 111 articles were found, and 44 articles were evaluated in full, and 23 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 06 studies with a high risk of bias and 31 studies that did not meet GRADE. Minimizing contraction appears to be the most important factor in ensuring an accurate impression for this technique. Digital printing has achieved high patient acceptance, reduces possible impression and master mold errors, reduces time in the chair, provides a three-dimensional image of the preparation, and ease of communication between the clinician and the laboratory. However, there is a dearth of scientific data regarding implant fingerprints and their accuracy. Research on implant fingerprinting has been limited to a few in vitro studies and case reports

Endometriosis according to the female population: a prospective observational cross-sectional study

Introduction: One of the problems that affects the female population of childbearing age or post-menopause is endometriosis, which is a chronic condition that affects between 2 and 17% of women of reproductive age. Objective: This study was conducted to verify the knowledge that female participants, from private practices or health insurance and the Unified Health System (SUS), have about endometriosis, aiming to obtain data that can support educational actions in public health policies. Methods: This study followed a prospective observational and cross-sectional model, following the STROBE rules. This study was carried out through an electronic questionnaire. It was carried out with a random sample of 204 female participants, 18 years of age or older. The form applied consisted of a questionnaire validated by the reliability of Cronbach's alpha coefficient. Pearson's Chi-Square test was performed, and the statistically associated variables presented p<0.05 (rejecting H0). The project was submitted to the Research Ethics Committee of the Unilago University, located in the city of São José do Rio Preto, São Paulo, Brazil. After approval under numbers 6,901,539. Through the analysis of a standardized research questionnaire, the aim is to obtain quantitative data that elucidate the objective of the research. Results and Conclusion: Knowledge of endometriosis among women showed a statistically significant difference between the variables public health (SUS) versus private health. A better understanding of the pathophysiology of endometriosis is imperative for the development of new therapeutic strategies that are continuous for both the diagnosis and treatment of endometriosis. A brief education program on menstrual health and endometriosis can improve knowledge and attitudes among women. Artificial intelligence can be an important tool for educating and informing patients about endometriosis, providing accurate and comprehensive answers to common questions, and facilitating a better understanding of the condition

Improving buccomaxillofacial surgical techniques and minimally invasive: a systematic review

Introduction: In minimally invasive there are several clinical studies with increasing expectations to establish treatment guidelines. Recently, advanced technology in the reconstruction of three-dimensional models based on computed tomography (CT), such as cone beam CT, has opened a new axis in the application of personalized and accurate diagnosis and has been increasingly used in the field of dentistry. Objective: This study aimed to analyze the evolution and consequent importance of improving surgical techniques and minimally invasive treatments in dentistry. It was hypothesized that there were statistically significant results on advances in minimizing trauma, providing patients with quality of life, and better aesthetics. Methods: The systematic review rules of the PRISMA Platform were followed. The search was conducted from June to July 2024 in the Web of Science, Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 139 articles were found. 26 articles were fully evaluated and 15 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 49 studies with a high risk of bias and 34 that did not meet GRADE and AMSTAR-2. Most studies presented homogeneity in their results, with X2=83.8%>50%. The maximum preservation of the integrity of the soft tissues (papillae and free and inserted gingival band) adjacent to the prosthetic spaces should be sought; as preservation of the alveolar bone ridge level. Based on the histological concept living tissues are formed by cells joined by thin elastic tissue and with nerve fibrils, capillaries, lymphatic and blood vessels. The disruption of these cells by surgical trauma provides the release of enzymes that delay healing. For this reason, surgical trauma should be minimized. There are many attempts to minimize the professional effort, reduce surgical time, and alleviate bleeding and inflammatory processes, edema, pain, and ecchymosis that can affect patients. Thus, the maximum preservation of the integrity of the soft tissues adjacent to the prosthetic spaces and the preservation of the level of the ridge of the alveolar bone to achieve a minimization of surgical trauma must be sought

Impact of maternal diabetes on fetal cardiac function: overview of clinical studies

This research is a review study on the clinical research looking at how maternal diabetes affects fetal heart function. It investigates the effects of various forms of maternal diabetes on fetal cardiac function and development, explores the underlying mechanisms of these effects, and talks about the therapeutic consequences of these results. In this study has discusses possible future paths for this type of study, as well as intervention and preventative techniques

Major approaches and clinical optimizations of zygomatic implants through guided surgery: a systematic review

Introduction: In the dental implant scenario, the graft to treat severely reabsorbed jaws is currently the gold standard procedure, but there are flaws in this procedure from 10.0 to 30.0 % are reported in the literature. Zygomatic implants have shown, in many cases, improved clinical outcomes compared to bone graft and represent an essential alternative for compromised maxillary bone. Objective: It analyzed the main approaches and clinical optimizations of zygomatic implants through guided surgery.   Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from November 2024 to January 2025 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 195 articles were found, and 48 articles were evaluated in full and 36 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 22 studies with a high risk of bias and 25 studies that did not meet GRADE and AMSTAR-2. According to the GRADE instrument, most studies presented homogeneity in their results, with X2=91.7%>50%. It was concluded the zygomatic implant is revolutionizing the procedure of implants in the posterior atrophic maxilla, eliminating the complications of bone augmentation and sinus elevation, with delayed scarring. Zygomatic implants have in many cases shown better clinical results compared to bone grafts and represent a possible gold standard for dental implants. Robotic placement of zygomatic implants has the potential to produce excellent results

Clinical outcomes of the importance of minimally traumatic tooth extraction for dental implant and aesthetic: a systematic review

Introduction: In the context of tooth extraction, this clinical practice is common for dentists, with the main causes of caries, periodontal disease, and coronal-radicular fractures. The choice for rehabilitation with implants has been growing, and to be carried out, it needs alveolar bone preservation at the implant site and adequate gingival contour, especially in aesthetic regions. However, the new techniques and instruments for minimally traumatic extraction still need to be analyzed, as little research has evaluated the success rate and limitations of these devices. Objective: It was developed a systematic review to highlight the importance of minimally traumatic tooth extraction for dental implants and aesthetics. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from November 2024 to January 2025 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: 130 articles were found, 32 articles were evaluated in full and 25 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 21 studies with a high risk of bias and 32 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=81.6%>50%. It was concluded that the use of precise and minimally traumatic techniques enabled satisfactory and functional aesthetic results, as well as improving the patient's aesthetics and self-esteem. The immediate implant placement procedure after tooth extraction preserves bone height and thickness, reduces treatment time and cost, in addition to maintaining the gingival architecture, being important for the aesthetic success of future prosthetic rehabilitation. Also, it presents success rates comparable to implants in fully healed edges, the extraction must be done in a minimally traumatic way, to preserve the maximum bone tissue. The horizontal defects present after the installation of the immediate implant, if they are less than or equal to 3mm, will heal with complete bone filling. However, if they are larger than 3mm, bone graft material and/or membrane should be used so that there is bone healing