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Acute effects of flywheel eccentric and traditional strength training on power output in male athletes: Post-activation potentiation approach
Bu araştırmanın amacı, flywheel (FW) ve inclened leg press (LP) yüklenmeler sonrası post aktivasyon potansyelinin (PAP) dikey sıçrama, quadriceps kas aktivasyonu ve çeviklik üzerinde akut etkilerini incelemektir. Araştırmaya 18-32 yaş arasında toplam 24 üniversite erkek sporcu öğrencisi gönüllü katıldı. Bu randomize kontrollü çapraz desene dayalı araştırmaya katılanlar en az 72 saat arayla bir alıştırma ve iki farklı deneysel prosedür uygulamışlardır: FW ve LP. Alıştırma oturumunda katılımcılara deneysel prosedürler anlatıldıktan sonra, EGZ A+ cevapladılar, vücut kompozisyonları ve 1 Tekrar Maksimum (1TM) belirlendi. Daha sonra FW, LP, maksimum istemli izometrik kasılma (MVC), dikey sıçrama (CMJ) ve Zig-zag agility testleri katılımcı tarafından uygulandı. İki deneysel oturumlarda ise sırasıyla; ısınma, Pre test: MVC, CMJ, Zig-zag çeviklik testleri, FW veya LP yüklenmesi (3 set x 6 tekrar), Post test: hemen sonra-15 sn (Post_0), 6 dk (Post_6), 12 dk (Post_12) ve 18 dk (Post_18) sonra Pre testleri tekrar uygulandı. Elde edilen verilen karşılaştırılması için Two Way ANOVA tekrarlanan ölçümler için varyans analizi (2 uygulama (FW ve LP) x 5 zaman (Pre, Post_0, Post_6, Post_12, Post 18) testi kullanıldı. İkili karşılaştırmalar için Bonferroni post-hoc testi kullanıldı. Araştırmamızda, iki farklı uygulama (FW ve LP) ile zaman (Pre, Post_0, Post_6, Post_12, Post 18) arasındaki etkileşim açısından CMJ [F(4,68) = 0.092, p = 0.985, 2 = 0.005], Zig-Zag [F(4, 68, p = 0.520, 2 = 0.038], M. Rectus Femoris MVC [F(4, 68) = 1.123, p = 0.353, 2 = 0.062], M. Vastus Lateralis [F(2.755,46.829) = 1.066, p = 0.369, 2 = 0.059], M. Vastus Medialis [F(2.780,47.258) = 0.480, p = 0.683, 2 = 0.027] sEMG değerlendirmelerin istatistiksel olarak anlamlı bir fark gözlenmemiştir. Sonuç olarak, Flywheel ve Incline Leg Pres egzersizleri bacak kaslarında benzer bir PAPE oluşturdukları söylenebilir. Ayrıca bu egzersizler sonrası yapılan 18 dakikaya kadar pasif dinlenmenin bir toparlanma olduğunu ancak her iki uygulamada da etkinin benzer olduğu görüldü.The aim of present study was to investigate the acute effects of post-activation potentiation (PAP) following flywheel (FW) and inclined leg press (LP) loading on vertical jump (CMJ), quadriceps muscle activation, and agility. A total of 24 male university athletes aged 18–32 voluntarily participated. In this randomized controlled crossover design study, participants completed one familiarization and two experimental (FW and LP) sessions, each separated by at least 72 hours. During the familiarization session, after the experimental procedures were explained, participants completed the PAR-Q+, and their body composition and one-repetition maximum (1RM) were assessed. Subsequently, participants performed FW, LP, maximal voluntary isometric contraction (MVC), CMJ, and Zig-zag agility tests. In each of the two experimental sessions, the following protocol was applied: warm-up; pre-tests (MVC, CMJ, Zig-zag agility test); FW or LP loading (3 sets × 6 repetitions); and post-tests conducted immediately after (Post_0), at 6 minutes (Post_6), 12 minutes (Post_12), and 18 minutes (Post_18), repeating the pre-test measures. To compare the collected data, a Two-Way Repeated Measures ANOVA (2 conditions: FW and LP × 5 time points: Pre, Post_0, Post_6, Post_12, Post_18) was used. Bonferroni post-hoc tests were applied for pairwise comparisons. The results showed no statistically significant interaction between condition (FW vs. LP) and time (Pre, Post_0, Post_6, Post_12, Post_18) for CMJ [F(4,68) = 0.092, p = 0.985, 2 = 0.005], Zig-zag agility [F(4,68), p = 0.520, 2= 0.038], M. Rectus Femoris MVC [F(4,68) = 1.123, p = 0.353, 2= 0.062], M. Vastus Lateralis [F(2.755,46.829) = 1.066, p = 0.369, 2 = 0.059], and M. Vastus Medialis [F(2.780,47.258) = 0.480, p = 0.683, 2= 0.027] sEMG measurements. In conclusion, both Flywheel and Incline Leg Press exercises appear to induce similar PAPE responses in the leg muscles. Furthermore, passive rest periods of up to 18 minutes following these exercises seem to support recovery, with both methods producing comparable effects
Solution-focused therapy for self-handicapping behaviors among Turkish high school students
Purpose: This randomized controlled trial examined solution-focused brief therapy (SFBT) effectiveness for reducing self-handicapping behaviors among Turkish high school students during the 2018-2019 academic year. Methods: Forty-five students (aged 14-16) scoring above 1 SD on the Self-Handicapping Scale were randomly assigned to SFBT intervention (n = 15), placebo control (n = 15), or waiting list groups (n = 15). The experimental group received 6 weekly 60-min SFBT sessions. Assessments occurred at pretest, posttest, and 6-week follow-up. Results: No significant between-group differences emerged at posttest (chi(2) = 3.588, p > .05). However, significant differences favoring experimental group appeared at follow-up (chi(2 )= 6.212, p < .05), particularly versus placebo (U = 34.50, p = .016, r = .46). Within-group analyses showed significant reductions for experimental group from pretest to follow-up (Z = -2.555, p < .05, r = .74). Discussion: SFBT effectively reduced self-handicapping with delayed benefits, supporting strength-based school approaches for at-risk adolescents
Effect of austenitizing heat treatment on microhardness and corrosion resistance of 1.4116 martensitic stainless steel
Martensitic stainless steels are utilized in applications requiring high hardness, low wear, and elevated corrosion resistance. Owing to their high alloying element content, they can be hardened through heat treatment. To achieve the desired mechanical properties and corrosion resistance, heat treatment parameters must be appropriately selected; the ratios of martensite, carbide, and retained austenite in the microstructure should be balanced. In this study, temperature and time parameters in the austenitizing heat treatment of 1.4116 (X50CrMoV15) martensitic stainless steel, commonly used in the knife manufacturing industry, were experimentally investigated to obtain an optimal microstructure, maximum hardness, and high corrosion resistance. Temperature values of 1,000 degrees C, 1,020 degrees C, 1,040 degrees C, 1,080 degrees C, 1,100 degrees C, and 1,120 degrees C, as well as durations of 180 s, 210 s, and 260 s, were examined. At lower temperatures, insufficient hardness was achieved due to incomplete austenite transformation and partial dissolution of carbides. At higher temperatures, grain coarsening and retained austenite formation led to a decrease in hardness. At the optimal temperature of 1,080 degrees C, significant carbide dissolution occurred, complete austenite transformation was achieved, and high-carbon martensite was formed, resulting in maximum hardness. In the time-based experiments, an increase in duration led to a reduction in retained austenite in the microstructure and an increase in hardness. From a corrosion resistance perspective, samples with higher hardness exhibited lower corrosion resistance; however, with increasing duration, corrosion resistance improved due to the activation of diffusion mechanisms.Yesilyayla Cutting Tools Metal Goods and Construction Industry and Trade Co. Ltd.
AR-GE-20-02
Investigation of antitumoral effectiveness of oral and local co-applied propolis in skin and subcutaneous tumors (melanoma and fibroma) of thoroughbridged Arabian horses: Case series
Bu çalışmada, Safkan Arap atlarında deri ve deri altı dokularda gelişen melanoma ve fibroma üzerine propolisin antitümöral etkisinin araştırılması amaçlandı. Çalışmada, hem sistemik (oral yolla) hem de lokal uygulanan propolisin klinik, hematolojik ve histopatolojik düzeyde oluşturduğu etkiler değerlendirildi. Deney grubunu oluşturan beş tümörlü Safkan Arap atına 3 ay boyunca günlük 150 mg/kg dozda ham toz propolis yemine karıştırılarak oral yolla verildi, aynı zamanda tümör üzerine 70% etil alkol içerisinde hazırlanan propolis tentürü lokal olarak uygulandı. İki adet sağlıklı ve tümörü bulunmayan dişi Arap atı kontrol grubu olarak kullanıldı. Tümör çapı ölçümleri, tam kan sayımı, biyokimyasal parametreler ve histopatolojik analizler yapılarak propolisin terapötik etkileri değerlendirildi. Malonomalı tümör çaplarında bir miktar azalma olmakla birlikte bu azalma istatistiki olarak önemli bulunmadı. Hematolojik sonuçlar genellikle referans aralığı ile kontrol grubu sonuçlarıyla uyumluluk göstermekle birlikte, WBC (p=0,014) için kan alınan dört dönem için ve detayda 0.Ay ile 2.Ay arasında düşmekte ve bu fark istatistiki olarak (p=0,009) anlamlıdır. NEU (p=0,003) için kan alınan dört dönem için ve detayda 0.Ay ile 2.Ay arasındaki düşüşün (p=0,001) WBC’de olduğu gibi anlamlı olduğu görülmektedir. HGB (p=0,026) için kan alınan dört dönem için ve detayda 2.Ay ile 3.Ay arasındaki düşüş (p=0,016) istatistiksel olarak anlamlı bulunmuştur. Biyokimyasal sonuçlar da genellikle referans aralığı ile kontrol grubu sonuçlarıyla uyumluluk göstermekle birlikte, TCHO (p=0,028) için kan alınan dört dönem için ve detayda 1.Ay ile 3.Ay arasındaki yükselme (p=0,020) anlamlı bulundu. CA (p=0,006) için kan alınan dört dönem için ve detayda 0.Ay ile 2.Ay (p=0,020) ve 0.Ay ile 3.Ay arasındaki yükselme (p=0,042) istatistiksel olarak anlamlı bulundu. Sonuç olarak, bu çalışma atlarda propolisin sistemik olarak kullanıldığı ilk çalışmalardan biridir. Propolisin atlarda herhangi bir olumsuz etkisi gözlenmemiştir. Propolisin belirtilen doz, uygulama yolları ve sürede, belirtilen tümör çapları üzerinde önemli bir etkinliği gözlenmemiştir. Bu çalışmaların detaylandırılarak daha yakın dönemde oluşmuş türmörlerde ve daha yüksek dozlarda propolis kullanılarak devam ettirilmesi uygun olacaktır.The aim of the study was to search antitumoral effects of propolis on melanoma and fibroma observed in cutaneous and subcutaneous of Arabian mares. Clinical, haematologic and histotpathologic effects of propolis were evaluated applicated both systemic (oral) and local. The experimental design involved a combined application of crude powdered propolis with feed administered orally (150 mg/kg/day) and alcoholic tincture of propolis (70%) applied locally to tumor surfaces for a three-month treatment period in five Arabian mares diagnosed with tumors. Two healthy mares used as the control group. Tumor sizes measurements, hematological, biochemical assessments, and histopathological evaluations were evaluated for therapeutic effects of propolis. However, there was a little decreasing in melanoma sizes, this differences were not significant. In addition, hematological results were generally consistent with reference range and control group results, but statistically, blood collected in four times for WBC (p=0.014), and in detail the decreasing between 0.Month and 2.Month (p=0.009) were significant. Blood collected in four times for NEU (p=0.003), and in detail the decreasing between 0.Month and 2.Month (p=0.001) were also significant. Blood collected in four times for HGB (p=0.026), and in detail the decreasing between 2.Month and 3.Month (p=0.016) were also significant. However biochemical results were also generally consistent with reference range and control group results, statistically, blood collected in four times for TCHO (p=0.028), and in detail the increasing between 0.Month and 3.Month (p=0.020) were significant. Blood collected in four times for CA (p=0.006), and in detail the increasing between 0.Month and 2.Month (p=0.020) and between 0.Month and 3.Month (p=0.042) were significant. As a result, the study is the first study for systemic uses of propolis, and no observed any adverse effects of propolis on horses. The propolis uses were not significant effective on tumor sizes with the applicated dose, application routes, application period. The studies that including antitumoral effecs of propolis in horses should search in detail with fresh melanoma tumors and higher doses
Multi-layered diaspora experiences: A qualitative study with third-generation Turks living in Berlin
Almanya’daki Türk diasporası, Avrupa’da en yoğun nüfusa sahip diasporik topluluklardan biridir. Türkiye’den Almanya’ya son yıllarda artan göç hareketliliği, yerleşik Türk toplumu ile yeni gelenler arasındaki ilişkileri ve karşılıklı algıları daha görünür hale getirmekte; bu karşılaşmaların diaspora içi ilişkileri anlamak açısından incelenmesi önem kazanmaktadır. Bu çalışmanın amacı, Berlin’de yaşayan ve Almanya’da doğup büyümüş üçüncü kuşak Türk bireylerin kimlik/aidiyet deneyimlerini ve diasporanın içsel dinamiklerini anlamaktır. Bununla birlikte, çalışmanın bir diğer amacı, üçüncü kuşağın son yıllarda Türkiye’den Almanya’ya göç eden yeni dalga Türk göçmenlere dair yaklaşımlarını ve Türk toplumuyla ilişkilerini keşfetmektir. Anlamak ve keşfetmek temel amaç olduğu için, bu araştırma, temel nitel araştırma deseni doğrultusunda tasarlanmıştır. Amaçlı örneklemle Berlin’de yaşayan, 18 yaş üstü üçüncü kuşak 12 katılımcıyla Haziran–Eylül 2025 döneminde yarıyapılandırılmış derinlemesine görüşmeler yapılmış; veriler içerik analiziyle çözümlenmiştir. Sonuçlar, diasporanın iç dinamiklerine, üçüncü kuşağın kimlik algılarına, yeni gelen Türk göçmenlere yönelik yaklaşımlarına ve Türk toplumuyla ilişkilerine ilişkin kodlar ve temalar üzerinden şekillenmiştir. Bulgular, üçüncü kuşak Türk bireylerin kimlik ve aidiyet deneyimlerinin tek bir eksende sabitlenmediğini; Almanya ile Türkiye arasında bağlamsal olarak değişen, ilişkisel ve çok katmanlı biçimde kurulduğunu göstermektedir. Ayrıca yeni dalga Türk göçmenlere ve Türkiye’de yaşayan Türklerle ilişkilere dair anlatılar, diaspora içinde benzerlik kadar mesafe ve sınır üretimlerinin de bulunduğuna işaret etmektedir.The Turkish diaspora in Germany is one of the diasporic communities with the densest population in Europe. The increased migration mobility from Turkey to Germany in recent years makes the relationships and mutual perceptions between the established Turkish community and newcomers more visible; examining these encounters in terms of understanding intra-diaspora relations is gaining importance. The aim of this study is to understand the identity/belonging experiences of third-generation Turkish individuals living in Berlin and who were born and raised in Germany, and the internal dynamics of the diaspora. In addition, another aim of the study is to explore the third generation’s approaches toward the new wave of Turkish migrants who have migrated from Turkey to Germany in recent years and their relationships with the Turkish community. Since understanding and exploring are the main aims, this research was designed in line with the basic qualitative research design. With purposive sampling, semi-structured in-depth interviews were conducted with 12 third-generation participants living in Berlin and over the age of 18 during the period June–September 2025; the data were analyzed using the content analysis technique. The results were shaped through codes and themes regarding the diaspora’s internal dynamics, the third generation’s perceptions of identity, their approaches toward newly arrived Turkish migrants, and their relationships with the Turkish community. The findings show that the identity and belonging experiences of third-generation Turkish individuals are not fixed on a single axis; they are constructed in a context-dependent, relational, and multi-layered manner between Germany and Turkey. In addition, narratives regarding the new wave of Turkish migrants and relations with Turks living in Turkey indicate that there are distance and boundary productions within the diaspora as much as similarity
Clinical practice of the endothelial activation and stress index and its modified versions in multiple myeloma and the effects on prognosis
Objective: Here, we aimed to evaluate the prognostic values of the endothelial activation and stress index (EASIX) and its derivatives, modified EASIX (mEASIX) and simplified EASIX (sEASIX), in patients with multiple myeloma (MM). Methods: The data of 134 newly diagnosed MM patients between January 2020 and December 2024 were retrospectively analyzed. Patients were divided into groups based on EASIX and its derivatives, and the outcomes of survival rates in groups were compared. Optimal cut-off points were determined using the receiver-operating characteristic analysis, and mortality predictive values of the scores were investigated. The independent prognostic factors were evaluated through univariate and multivariate Cox regression analyses. Results: The optimal cut-off point for EASIX was detected as >1.03, and survival times were significantly shorter in patients with higher EASIX scores (p 26.5, showing higher specificity (area under curve (AUC) = 0.663; p = 0.003). The sEASIX score predicted lower mortality (AUC = 0.586; p = 0.123). In multivariate analysis, high EASIX scores, not performing autologous stem cell transplantation, and not receiving immunomodulatory therapy were identified as independent negative prognostic factors for survival. Conclusion: EASIX, especially mEASIX, is a valuable prognostic tool for predicting survival in MM patients. EASIX can be easily integrated into clinical practice due to its simple computability and reliance on commonly used laboratory parameters. However, larger prospective studies are needed to determine how these scores can be integrated with traditional prognostic systems such as the International Staging System (ISS) and Revised-ISS