Core Concept of Ayurveda for Longevity of Healthy Life

Ayurveda is our ancient line of treatment, which is followed from many years ago. It contains the information from the Birth to Death of human being health itself. Give knowledge about the living pattern of human being and also give information about the treatment of various diseases at that time to survival of human being. From which we are able to decode half of the knowledge given by our ancient masters / Acharyas. Many searches for the same are going on too. Our ancestors at that time lived healthy and disease free life without having any machines and instruments which we are using now days. They give importance to each phase of life and also give the information to take care of their health at every phase of life from the mother womb to death of the individual. Here is summary about how we can follow their footstep so that we make sure that our coming generation and present generation live healthy and disease free life. Sanskaras that we used to follow at that time and also how we can manifest them in today life also, such as Jatkarma, Karnavedana, Achara rasayana, Ritucharya. By just following these thumb rule one can attain healthy life easily

A Clinical Study of Kanchanara Patra Phanta in Management of Hypothyroidism

Hypothyroidism is a common endocrine disorder. Primary Hypothyroidism is up to 8–9 times more common in women than in men, and the prevalence increases with age, with a peak incidence between the ages of 30 and 50 years. According to Ayurveda, this disease is termed as Galaganda. Acharya Sushrutha opines that a swelling in the neck, big or small hanging-like scrotum is defined as Galaganda; this disease, is characterized by vitiation of Agni along with Kapha and Vata dosha. Various Shodhana and Shamana chikitsa have been mentioned for Galaganda. Kanchanara (Bauhinia purpurea Linn) is one such drug mentioned for the treatment of Galaganda by Acharya Bhavaprakasha. As there is an ambiguity about effective and successful treatment for Hypothyroidism due to its varying signs and symptoms, it necessitates finding an effective formulation for treating Galaganda (Hypothyroidism). Aim: To assess the efficacy of Kanchanara patra phanta in Hypothyroidism. Materials and methods: This study was a randomized, open labeled, non-controlled, interventional clinical trial with before and after evaluation of data in a single group. A single group of 30 study samples was recruited based on the assessment criteria and study was conducted for a total of 30 days period; Assessment of the condition was done with regular follow-ups of day 1, 15 and 30. Conclusion: 30 days (twice daily) of internal administration of Kanchanara patra phanta showed highly significant efficacy in pacifying the symptoms and reducing the levels of TSH

Exploring the Efficacy of Nasya Therapy in the Management of Nidranash (Insomnia): An Ayurvedic Perspective

This study explores the efficacy of Nasya therapy in the management of Nidranash (insomnia) from an Ayurvedic perspective. Insomnia, a prevalent sleep disorder, significantly impacts the quality of life and overall health. Conventional treatments often involve pharmacological interventions that can lead to dependency and adverse effects. Ayurveda, the traditional Indian system of medicine, offers alternative approaches, with Nasya therapy being one of the prominent treatments for Nidranash. Nasya involves the administration of herbal oils or medicinal substances through the nasal passages, targeting the central nervous system and promoting relaxation and sleep. This paper reviews the principles of Nasya therapy, the herbal formulations used, and the underlying mechanisms contributing to its effectiveness. Clinical evidence and case studies are examined to assess the outcomes and benefits of Nasya in treating insomnia. The findings suggest that Nasya therapy, with its holistic approach and minimal side effects, presents a viable and effective treatment for insomnia, aligning with the Ayurvedic philosophy of restoring balance and harmony within the body. Further research and clinical trials are recommended to substantiate these findings and integrate Nasya therapy into mainstream insomnia management protocols

A critical Review of Aalochak Pitta with Special Reference to Padabhyanga

Doshas are Sort to be specific Vata, Pitta and Kapha. Sushruta called it as Tristhuna (like house depends on points of support (Sthuna)) Similar way body depends on this Tristhuna. Pitta addresses energy intensity or fire in body and also performs activities like fire in body. Pitta has Agni Mahabhuta and Pitta in body which is situated in the structure of Agni is liable for assimilation and digestion of ingested food. Aalochak Pitta helps in great vision and it implies the Pitta which is answerable to the vision. Drishti or vision is seat of Aalochak Pitta. Drishti implies vision which empowers us to see things around us. There are two types of Aalochak Pitta they are Chakshu Vaisheshik Aalochak Pitta and Budhhi Vaisheshik Aalochak Pitta. Padabhyanga is the name for massaging and applying oil to the feet. Padabhyanga (foot massage) is one of the parts of Dinacharya. According to Charak and Vagbhat Padabhyanga is Drishtiprasadak and According to Sushruta it is Chakshushya. Padabhyanga can be done with Ghrita and Taila. The reflexology point of eye are situated on under sides of second and third toes of foot this maintain the eye health. Padabhyanga might be nourishing or stimulation effect on eyes and improving function of eyes. Ashtang Hridaya identifies 4 major nerves in feet that connect to eyes. These nerves in maintaining good eyesight and relieve eyestrain when subjected to soothing therapies like Padabhyanga. Hence the therapy on Pada effects on Netra. Here is an attempt to study the effect of Padabhyanga on Aalochak Pitta

Standardization of Herbal Drugs: Vacha (Acorus Calamus Linn.) and Dvipantara Vacha/Chopchini/China Root (Smilax China Linn.) with their In-Vitro Antimicrobial Potential

Ayurveda is a part of the "science of life," which is the study of traditional medicinal plants that are used and found worldwide to treat and prevent various illnesses. There is increasing awareness and general acceptability of the use of herbal drugs in today’s modern practice. Around 80% of the world\u27s population relies on herbal treatments and products for health, despite their unconventional uses. This growth in the usage; abuse and adulteration of herbal products has also resulted in consumers and manufacturers being disappointed, and in extreme cases, the repercussions are lethal. Standardization of herbal medicines is the process to ensure the efficacy and safety of medicinal plants. Vacha (Acorus calamus Linn.) and Dvipantara vacha/ Chopchini/ China root (Smilax china Linn.) are among the four varieties of Bhavaprakash Nighantu. Both drugs are used in disorders like epilepsy. Plants contain a huge diversity of chemical compounds known as secondary metabolites. This study investigates the phytochemicals and in-vitro antimicrobial potential of Vacha and Dvipantara vacha; particularly focusing on their antibacterial and antifungal activities against specified bacteria and fungi namely Staphylococcus aureus and Candida albicans

Smart Spectrophotometric Methods for the Determination of Chlorzoxazone and Paracetamol Form Tablets

Two simple, accurate and precise spectrophotometric methods have been introduced for the simultaneous measurement of chlorzoxazone and paracetamol in a combined tablet form. The first method is a graphical spectrophotometric method utilizes the data taken at multiple wavelengths to generate linear plots, from which the concentration of analytes can be determined, the second method is dual wavelength spectrophotometric method which is based on selecting two wavelengths for each drug to ensure that the absorbance difference is zero for the other drug. In the graphical method the absorbance was measured at 240, 260, 280 and 300 nm, while in the dual wavelength method; 224.5 nm and 264 nm were chosen for chlorzoxazone determination since paracetamol shows equal absorbance at these wavelengths. Conversely, for paracetamol determination, wavelengths 234.5 nm and 273.5 nm were selected, with chlorzoxazone having zero absorbance difference at these wavelengths. Both drugs adhere to Beer-Lambert’s law within a concentration range of 4–20 µg/mL. The methods accuracy and precision were assessed following the International Conference on Harmonization (ICH) guidelines. Recovery studies further validated the method\u27s accuracy. The precision of the method was demonstrated by low relative standard deviations (% RSD) less than 2%, indicating good repeatability and intermediate precision. Method accuracy was confirmed by the agreement between the determined and actual contents, also with % RSD less than 2%. The two methods enable direct analysis of chlorzoxazone and paracetamol in commercially available tablet formulations without the need for prior separation

Critical Review of Ayurvedic Herbs in Treatment of Gynecological Problems

Joint pain is a common complaint among the elderly. The 62 year-old male patient in this case study has osteoarthritis in his knee joint and has been enrolled in an Ayurvedic program for treatment. A type of Vatavyadhi called Janusandhigatavata is described in Ayurveda and is almost identical to osteoarthritis of the knee joint. In this case study, the impact of Janubasti combined with Mahanarayanataila and Dashmoolakwathnadi-Swedana is evaluated. The patient has been advised to have two therapy sessions, each lasting six days, with a six-day break in between. According to the study, there has been a noticeable improvement in subjective parameters such as joint pain, Sandhi shoola, and pain during flexion and extension of the joint in Vatapurnadritisparsa, Prasaranakkunchana pravritisavedana. Following the study, Sandhi Shotha (joint swelling) is totally resolved

Method Development and Validation of Cefixime by Using RP-HPLC in Pharmaceutical Formulations

Analytical method development and validation are ongoing and interconnected activities that are essential in research and development, quality control, and quality assurance departments. They involve the creation and testing of analytical procedures to assess equivalence and manage risks effectively. These procedures are crucial for establishing specific acceptance criteria for products and ensuring the reliability and consistency of results. Validations are essential in assessing whether an analytical procedure is appropriate and reliable for its intended purpose. Literature survey reveals that the analytical methods based on UV spectrometry, RP-HPLC and HPTLC for the determination of Cefixime individually and combination with others drugs . The methods were validated according to ICH guidelines in terms of accuracy, precision, lod, and other aspects of analytical validation. The developed analytical methods for cefixime have been designed to be straightforward, making them easy to perform. They have also demonstrated high sensitivity, enabling the detection and quantification of cefixime at low concentrations. This sensitivity is crucial for accurately determining the amount of cefixime present in bulk samples or tablet formulations

The Combine Effect of Suvarnaprashan with Speech-Language Therapy in Children with Delayed Speech and Language Disorder

Suvarnaprashan is ancient oral vaccination technique describe Ayurvedic texts. Delayed in acquiring language are most common symptoms of childhood developmental disability affecting around 5 to 10% of all children. The effectiveness of Suvarnaprashan in various developmental disabilities in children was reported earlier studies. However, its effectiveness for children with pure delayed speech and language disorder without any associated developmental difficulties was not studied previously. Hence, the study taken with aim of the combine outcome of Suvarnaprashan with speech-language therapy in children with delayed speech and language disorder. Total no. of 50 participants with early diagnosed delayed speech and language disorder with age range from 02 to 05 were included for this study. The participants were divided in two subgroups in which group A underwent for speech language therapy only and group B underwent for both speech-language therapy and Suvarnayaprashan sanskara. Children with delayed speech and language disorder showed significant improvement with Speech language therapy plus Suvarnayaprashan intervention compare to speech and language therapy alone. Suvarnaprashan can be utilized effectively as a therapeutic tool for children with delayed speech and language disorder. It is very simple, cost effective, infrastructure compatible, safe and prevention–centric approach. Hence, it should be adopted globally as immunization program also for preventive measure of delayed speech and language disorders and disability. The present study opened new dimensions and need of further research in different area of disability with large sample and long term follow up

Method Development and Validation of Lorazepam by Using RP-HPLC in Pharmaceutical Formulation

High pressure liquid chromatography (RP-HPLC) is a column chromatographic technique employing high pressure pump to pass both mobile phase and sample mixture through stationary phase column and perform efficient separation. A C-18 column with mobile phase containing Acetonitrile: methanol (80: 20) was used. The flow rate was 1.0ml/min. and were monitored at 210 nm. The retention time for Lorazepam was 1.3 min. The method was validated for linearity, accuracy, precision, limit of detection. The Mean percent recovery of Lorazepam from tablet formulation was found to be 94.80 %