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    « Piccioli (CE, 17 janvier 1923) »

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    La chalandise universitaire

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    International audienc

    Numerical Simulation of a Valorisation-Oriented Hybrid Process for the Bio-Oil-Related Separation of Acetol and Acetic Acid

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    International audienceBiomass as a whole offers a more diverse potential for valorisation than any other renewable energy source. As one of the stages in the separation of bio-oil involves a liquid mixture of acetol and acetic acid, and as both components are particularly well suited for valorisation, a hybrid method was developed for their separation with a high purity level through an approach combining liquid–liquid extraction and distillation. In order to design and simulate the flowsheet, the ChemCAD 7.0 simulation software was used. Sensitivity analyses were carried out to investigate the influence of the different parameters in the distillation columns, such as the reflux ratio, the feed stage location, and the vapour/bottom molar flow ratio. The effect of different extractants and of their excess on the separation process, as well as the possibility of regenerating the extractant, was also studied. Tri-n-octylamine was accordingly selected as a separating agent that was fully recycled. The end result for separating an initial 48/52 wt% acetol/acetic acid liquid mixture was acetol with a purity of 99.4 wt% and acetic acid with a purity of 100 wt%

    Un compromis modernisateur. La santé au travail dans la fonction publique comme contrepartie à la réforme de l’État

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    International audienceBased on the use of multiple sources (trade union, regional public administration, French government), this article contributes to a social history of civil servants, as yet little documented regarding the damage on public workers’ health. It examines the way in which issues relating to the establishment of Hygiene and Safety Committees (CHS) in the public administrations discussed, especially in the context of "State modernization" projects during the Mitterrand years. It also sheds a light on the recognition of asbestos exposure as a problem for civil servants. This article is based on a multi-scalar approach, drawing on both national and local archives, as well as interviews with former employees of the Tripode administrative building in Nantes.Grâce au croisement de différentes sources (syndicales, préfectorales, ministérielles), cet article contribue à une histoire sociale des fonctionnaires, encore peu renseignée sous l’angle des atteintes à leur santé. Il revient sur la manière dont les enjeux relatifs à la mise en place des Comités d’hygiènes et de sécurité (CHS) dans la fonction publique sont discutés dans le contexte particulier des projets de « modernisation » des administrations publiques au cours des années Mitterrand, tout en éclairant à la mise à l’agenda du risque amiante auxquels sont exposés des fonctionnaires. Cette démarche repose sur une approche multiscalaire, des archives nationales et locales sont mobilisées, ainsi que des entretiens menés avec d’anciens agent·e·s du bâtiment administratif du Tripode, à Nantes

    Development and evaluation of a decision aid for women eligible for organized breast cancer screening according to international standards: A multi-method study

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    Backgroundand purpose:In France, women lack information to make a shared decision to start breast cancer screening. Decision aids are useful to facilitate this discussion, yet few meet international standards. The objective of this project was to build, validate and measure the quality of a decision aid for organized breast screening in France, in line with international standards, intended for both women and healthcare professionals.Materials and methodsThis mixed-methods study was conducted between January 2017 and June 2022. The prototype was developed from a qualitative study, systematic review and targeted literature review and alpha tested during two Delphi rounds. Readability was evaluated with the Flesch score and content with International Patient Decision Aid Standards Instrument (IPSASi).ResultsAn online decision aid, accessible at www.Discutons-mammo.fr, written in French was developed. The content included eligibility, information about breast screening the advantages and disadvantages of screening, patient preferences and a patient-based discussion guide using text, infographics, and videos. The Flesch readability test score was 65.4 and the IPDASi construct quality score was 176 out of 188.ConclusionsThis decision aid complies with IPDASi standards and could help women eligible for breast screening in France make a shared decision with a specialized healthcare professional about whether or not to participate in organized breast screening

    Algebraic K-theory of real topological K-theory

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    52 pages, 12 figures, 1 table. Conjecture B from v1 is proved in v2, along with other improvementsWe determine the A(1)-homotopy of the topological cyclic homology of the connective real K-theory spectrum ko. The answer has an associated graded that is a free F_2[v_2^4]-module of rank 52, on explicit generators in stems -1 \le * \le 30. The calculation is achieved by using prismatic and syntomic cohomology of ko as introduced by Hahn-Raksit-Wilson, extending work of Bhatt-Morrow-Scholze from the case of classical commutative rings to E_\infty rings. A new feature in our case is that there are nonzero differentials in the motivic spectral sequence from syntomic cohomology to topological cyclic homology

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