Enzymatic treatment of plant proteins in combination with algae-based nutraceutical inclusion in aquafeeds improves growth performance and physiological traits in the greater amberjack (Seriola dumerili)

This study aimed to evaluate, following two different and sequential feeding trials, the effects of partial substitution of fish meal by 44.5 % of plant proteins (similar to 50 % of total protein inclusion) on growth performance, intermediate metabolism, well-being, and muscle chemical composition in the greater amberjack (Seriola dumerili). Additionally, the benefits of performing a previous enzymatic treatment on the plant ingredients before elaborating experimental aquafeeds (Trial II) compared to using untreated plant ingredients were also assessed. Three isoproteic (63 % protein, CP) and isolipidic (18 % crude lipid, CL) diets were used in each experiment: i) a control diet (CTRL), with 75.5 % of protein from marine origin; ii) two experimental diets, with 44.5 % of plant proteins (PP and PPe for Trial I and II, respectively); and iii) the PP/PPe diets supplemented with 3 % of an algaebased functional additive produced by Lifebioencapsulation S.L. (PP-LB and PP-LBe for Trial I and II, respectively). The results showed that using vegetable ingredients enzymatically treated before the production of aquafeed allows the partial substitution of dietary animal marine protein without affecting, or even improving the fish growth performance. The algal-based functional additive did not improve the fish growth when incorporated in plant protein-based diets, although it seems to provide a protective effect to overcome the impairment produced by the first contact of pre-treated vegetalized aquafeeds with the gastrointestinal tract in juvenile amberjack. Moreover, the LB additive could provide other benefits in the long term both in fish fed on diets elaborated with untreated and pre-treated plant ingredients, as evidenced by the level of cortisol released, the protection against oxidative stress, and the improvement in the chemical composition of muscle compared to the fish fed the plant-based diet without the functional additive. These findings demonstrate that the combination of an enzymatic pre-treatment of plant proteins together with the use of nutraceuticals from algae-based additives is a potential tool for more sustainable aquaculture of greater amberjack, a carnivorous species of high commercial interest.131,0593,9Q1Q1SCI

Evaluación de la enfermedad hepática relacionada con Fibrosis quística en una cohorte pediátrica.

Background: Cystic fibrosis (CF) is an autosomal recessive, chronic, potentially lethal genetic disease. CF manifestations are due to mutations in the CF transmembrane receptor transporter (CFTR) gene which codes for a protein (CFTR) that acts as an anion transporter, mainly chlorine, at epithelial cells where it is expressed. Cystic fibrosis related liver disease (CFRLD) includes a spectrum of hepatobiliary manifestations whose diagnosis and follow-up remains a challenge. Methods: Cross-sectional, descriptive study from 10 Spanish Cystic fibrosis Units. Clinical and biochemical data obtained. Patients categorized into 3 groups according to liver involvement based on ESPGHAN 2017 criteria. Liver stiffness assessed by transient elastography (TE) and findings from abdominal ultrasound recorded. Statistics performed using SPSS v25.0. Results: We obtained hepatic TE data from 155 pediatric CF patients. Forty-four classified as CFRLD, 38 (86%) had CFRLD without cirrhosis and 6 (14%) had cirrhosis. Fourteen patients without CFRLD (12%) had ultrasound abnormalities. Mean liver elastography value (kPa) was 4.7 (3.5-5.3) in non-CFRLD and 6.09 (4.4-6.7) in CFRLD (p=0.01;Tstudent [T]). Conclusions: CFRLD is common in children with CF. Transient elastography is a useful method for diagnosis and follow-up, as higher values of TE are found in patients with CFRLD.Antecedentes: La fibrosis quística (FQ) es una enfermedad genética autosómica recesiva, crónica y potencialmente letal. Las manifestaciones de la FQ se deben a mutaciones en el gen del transportador del receptor transmembrana de la FQ (CFTR), que codifica una proteína (CFTR) que actúa como transportador de aniones, principalmente cloro, en las células epiteliales donde se expresa. La enfermedad hepática relacionada con la fibrosis quística (EHFQ) incluye un espectro de manifestaciones hepatobiliares cuyo diagnóstico y seguimiento sigue siendo un reto. Métodos: Estudio descriptivo transversal de 10 Unidades de fibrosis quística españolas. Obtención de datos clínicos y bioquímicos. Pacientes categorizados en 3 grupos según afectación hepática en base a criterios ESPGHAN 2017. Rigidez hepática evaluada mediante elastografía (TE) y se registran hallazgos de la ecografía abdominal. Estadística realizada mediante SPSS v25.0. Resultados: Se obtuvieron datos de TE hepática de 155 pacientes pediátricos con FQ. Cuarenta y cuatro se clasificaron como CFRLD, 38 (86%) tenían fenotipo de afectación hepática sin cirrosis y 6 (14%) tenían cirrosis. Catorce pacientes sin CFRLD (12%) presentaban anomalías ecográficas. El valor medio de la elastografía hepática (kPa) fue de 4,7 (3,5-5,3) en los pacientes sin CFRLD y de 6,09 (4,4-6,7) en los pacientes con CFRLD (p=0,01;Tstudent [T]). Conclusiones: La CFRLD es frecuente en niños con FQ. La elastografía hepática es un método útil para el diagnóstico y seguimiento, ya que se encuentran valores más altos de TE en pacientes con CFRLD.70,2632,2Q3Q3SCIE11,

Is the endemic <i>Phoenix canariensis</i> H. Wildpret an orthodox species? Implications for its conservation

Seed banks (gene banks) have become essential for the conservation of genetic biodiversity in natural ecosystems. Seed preservation is especially important for threatened species, since seeds are the primary genetic material used to reintroduce plant species. Knowledge of the desiccation tolerance of each species is relevant for selecting the best method for ex situ conservation, but it is not always available. Currently, the categorisation of the seed storage behaviour of the Phoenix species as orthodox, recalcitrant or intermediate, remains uncertain. This study uses four accessions of the endemic species from Canary Island Phoenix canariensis H. Wildpret, with storage times ranging between 2 and 28 years. Germination tests were carried out to measure seed viability over time, desiccation tolerance and the possible impact of seed storage on viability. The germination results differed for seeds after 192 days in a greenhouse. Accessions stored in the seed bank at -20 degrees C and 15%RH for 17 years showed a high germination percentage (72%). In contrast, accessions stored under unsuitable conditions showed a 0% germination. These results indicate the orthodox seed storage behaviour of P. canariensis. In addition, it supports the good state of conservation of the material stored in the Seed Bank of the Botanical Garden Viera y Clavijo and the reliability of the temperature and humidity conditions in which the seeds of P. canariensis have been stored. In addition, the results are relevant in order to manage the conservation of this endemic species from the Canary Islands.9190,3390,9Q3Q4SCIE11,

Perceptions on the Implementation of aSchool Nursing Pilot Programme in theCanary Islands: A Qualitative Study

This version is not peer-reviewed1

Estilometría TIP: enhanced text analysis tool with customisable metrics for Spanish texts

Stylometric analysis is a tool across the social sciences and humanities, aiding disciplines like education, psychology, history, anthropology, and linguistics. However, most tools are developed for English, limiting their effectiveness for Spanish texts, which involve complex inflections. This paper addresses this gap by introducing Estilometría TIP, a web-based tool specifically designed for the stylometric analysis of Spanish texts. Estilometría TIP overcomes the challenges posed by Spanish’s inflected forms through two primary functionalities. First, it offers customizable metrics: researchers can define and compute their own metrics using a configuration file, allowing them to tailor their analyses to specific research needs across different fields. This feature dynamically adjusts the user interface, adding or modifying menus to facilitate seamless exploration of customized results. Second, Estilometría TIP incorporates Lexicon TIP, a highly accurate lexical recognition service for Spanish with an accuracy of over 99.8%. Lexicon TIP draws on a comprehensive database of more than 320,000 lemmas and 8 million inflected forms, accounting for variations in number, gender, superlatives, diminutives, augmentatives, derogatory terms, and verb conjugations. Two key algorithms enhance this functionality: prefix detection, which accurately identifies prefixed words (e.g. ‘predeterminar’), and enclitic pronoun identification, which handles verb forms combined with enclitic pronouns (e.g. ‘comiéndotelas’).170,342Q2ESCI9,3ERIH PLU

Practices Related to Bladder Catheterisation Among Swedish Health Professionals: A Questionnaire Survey

Bladder catheterisation is an invasive procedure that must adhere to precise guidelines established by authorities, hospitals or nursing associations to prevent or minimise associated complications. Research indicates that a significant portion of infections could be averted through dedicated periodic training, monitoring of adherence, optimising workloads and innovating in the development of products designed to mitigate risks or enhance ease of use. This study aims to explore the behaviour of nurses in Sweden concerning bladder catheterisation. An anonymous survey was distributed to groups of nurses in Swedish hospitals and healthcare centres. The survey was designed by an expert nurse team and was meticulously prepared and reviewed by a Swedish physician to ensure content validity, comprehension and clarity. A total of 910 nurses participated in the survey. When questioned about whether they are supervised for guidelines compliance when inserting a urinary catheter, 42.0% admitted to not doing so. In fact, only 9.3% of the respondents claimed that they always receive assistance from a colleague during the catheterisation procedure. Nearly 90% of the participants indicated that they could not consistently maintain sterility during catheter insertion, with the primary source of stress being time pressure during the procedure (21.3%). Among those surveyed, 70.4% acknowledged that, in their last 10 catheter insertions, they inadvertently spilt urine on materials at least once, while 27.7% reported spillage on the bedding and 16.5% on individuals. When asked about the potential advantages of a new catheter with an integrated valve, the most significant advantage cited was the reduced risk of urine leakage (63.0%), followed by the convenience of not having to connect a urine bag or plug (52.1%), and the improved ease of collecting urine samples (42.3%). Only 4.9% of respondents did not identify any potential advantages of this device. The correlation analysis showed an inverse relationship between both the level of stress and experience in bladder catheterisation (Spearman's correlation coefficient = -0.413, p value < 0.001) and the level of stress and the frequency of external help during the catheterisation process (Spearman's correlation coefficient = -0.265, p value < 0.001). The study's findings reveal a lack of supervision during catheterisation and the excessive workload or understaffing that often compels nurses to perform the procedure without the assistance of a colleague. These factors may underlie the insufficient adherence to guidelines and protocols, which can result in errors during insertion, thereby increasing the risk of non-aseptic insertion and occupational hazards. It appears essential to invest in organisational changes, provide continuous training for their staff and prioritise the development and innovation of new devices to aid healthcare workers in catheter management or addressing the issue of CAUTI from a multifactorial perspective.1

Módulos VIII. Parte 2. Experiencias integradas. Los cuidados a la persona con cáncer

&lt;p&gt;M&oacute;dulos te&oacute;ricos de la asignatura CEA-I&lt;/p&gt

La transición del monopolio al libre mercado del tabaco. Experiencias comparadas en Canarias, Filipinas, Cuba y otros espacios americanos

Desde hace siglos, el tabaco ha generado una importantísima actividad económica. Fue fuente imprescindible de recursos para el Estado y un elemento sustancial en las políticas de vertebración de los imperios atlánticos ibéricos, llegando a situarse solo por detrás de los metales preciosos en el valor de los trasvases del Nuevo al Viejo Mundo, en el periodo entre 1782 y 1796. Durante el siglo XIX continuó siendo uno de los ejes básicos de los presupuestos del Estado. La investigación que aquí se presenta, se ocupa, como marco cronológico de referencia, de la última parte del siglo XVIII y del siglo XIX, que es cuando se produce en España el tránsito de imperio a nación colonial. Es de gran interés la valoración del tránsito del monopolio del tabaco en la periferia (Cuba, Canarias y Filipinas) a un estado de libre comercio y producción, mientras el marco monopolístico se mantiene en la metrópoli. La lectura comparada entre las regiones periféricas escogidas nos permite entender mejor la nueva articulación imperial y el propio nacimiento del Estado liberal en España.39