La liveness in prospettiva transdisciplinare. Un approccio integrativo al "dal vivo" tra arti performative e media

Il saggio introduce il tema della liveness in prospettiva transdisciplinare tra arti performative e media. In particolare avanza una proposta concettuale che integra le teorie e le analisi sul dal vivo che si concentrano sull'esperienza del "dal vivo" e sulle qualità dipendenti della continuità spazio-temporale con l'evento con la concezione della liveness come "discorso" in prospettiva costruttivista

The Background of the Gioconda: Geomorphological and Historical Data from the Montefeltro Area (Tuscan–Emilian Apennines, Central Italy)

This work combines geomorphological and historical research to decode the landscape in the world’s most famous painting: the Gioconda. The background of the painting was analysed in detail, and numerous morphological correspondences with the Montefeltro area in Central Italy were found. The upper valley of the Senatello stream features the Fumaiolo Massif, renowned for its springs that feed the River Tiber. The region is composed of the limestones and sandstones of the San Marino and Monte Fumaiolo Formations, alongside clay formations from the “Valmarecchia Nappe”. This lithological variety, the intense fracturing of the limestone rocks, and climatic and tectonic events during the Middle to Upper Pleistocene produced a complex and varied geomorphology. The landscape is marked by large landslides and significant debris deposits, reflecting its recent evolution. The painting, as well as historical documents and Leonardo’s drawings from his time in the Romagna region, provide evidence of a large lake beneath Mount Aquilone. The area was affected by a significant change in the morphology of the slopes, probably caused by a landslide that occurred in the period 1500–1700, a period characterised by climatic and tectonic upheavals, which may have led to the disappearance of the lake

First-in-class inhibitors of SbnA reduce siderophores production in Staphylococcus aureus

Siderophores production, along with heme scavenging by hemophores, is one of the main mechanisms exploited by bacteria to achieve iron supply. Staphylococcus aureus produces two main siderophores, staphyloferrin A (SA) and staphyloferrin B (SB), with the latter produced only by the most invasive, coagulasepositive S. aureus strains. Along the seven steps of SB biosynthetic pathway, SbnA catalyzes the crucial formation of the intermediate N-2-amino-2-carboxyethyl-L-glutamate from L-O-phosphoserine and glutamate. Our functional characterization of the enzyme highlighted that citrate inhibits SbnA with a Ki in the order of magnitude of the physiological concentration of the metabolite. We searched for inhibitors of SbnA within citrate analogues and identified 2-phenylmaleic acid (2-PhMA) as the best hit, with a Ki of 16 ± 2 μM and a mechanism of inhibition which is competitive with L-O-phosphoserine for active-site binding. The methyl ester of 2-PhMA at 2 mM concentration resulted effective in inhibiting siderophore biosynthesis in S. aureus. These results pave the way for the discovery of promising inhibitors of iron acquisition that might find application as innovative antimicrobials

Statuti e consuetudini locali. Il caso del diritto municipale romano

This contribution explores the role of local customs in the formation of the 1363 municipal Statute of Rome, a crucial text in the history of medieval Roman municipal law, long negled by legal historiography. Through the analysis of documentary and doctrinal sources, the essay highlights how Roman customs, particularly those relating to civil law, were integrated mainly in Book I of the Statute and examines the relationship between the enactment and the subsequent disappearance of the written collection of those customs, suggesting a causal relationship. Finally, the essay proposes an original reconstruction of the normative stratification of medieval Roman municipal law, addressing the debated question of the existence of an “ancient Statute”

From Big Farms to Big Pharma? Problematizing science-related populism

Skepticism about health/vaccination policies during Covid-19 was considered a key example of “science-related populism” mainly based on far-right case studies. However, critics also spread among various left-wing and environmentalist milieus, which represents an understudied phenomenon. Relying on different strands of scientific literature, and on a qualitative research design aimed both to take account of the political heterogeneity within this critical area and to deepen its links with environmentalism, we aim to highlight the limits and normative implications of its interpretation as solely populism, and to contribute to the elaboration of a different interpretive model. Qualitative and frame-bridging analysis highlighted the consolidation of worldviews in clear opposition to hegemonic values, where the criticism of science finds a more appropriate explanation in a denunciation of the intrusiveness of capitalism in science production, as well as in a rejection of “reductivism” and a claim to self-determination that extend from ecological to health issues

Turris Babel e la grafica delle riviste di architettura Turris Babel und die grafische Gestaltung von Architekturzeitschriften

Il contributo racconta e analizza in modo critico le scelte grafiche relative alla rivista Turris Babel dalla sua fondazione fino ad oggi contestualizzandola nell'ambito della storia del progetto grafico ed editoriale nazionale e internazionale. This contribution critically analyzes and recounts the graphic design choices made for Turris Babel magazine, from its founding to the present day, contextualizing them within the history of national and international graphic design and publishing

Land scarcity, sustainable uses and environmental policies.

that can either be used for food consumption, resulting in pollution, or invested in natural capital. Land scarcity imposes a quantity constraint that creates a trade-off between these alternative uses. This constraint shapes the dynamics of the system, influencing its differential equations and leading to a differential–algebraic system of equations (DAE). This approach represents a novelty compared to environmental dynamic models that rely solely on differential equations. Using this analytical framework, we show that shadow prices and stocks are closely interconnected and must be determined simultaneously. We use the DAE system to explore the impact of supranational policies aimed at achieving broader environmental goals on land allocation in the small economy. We derive two main results. First, the relative effectiveness of policy instruments is determined by the pollution intensity of consumption: when pollution intensity is low, incentives that promote land investment in natural capital are more efficient; conversely, when pollution intensity is high, regulatory measures that limit land use for consumption become more effective. Second, although temporary policies do not affect the long-run steady state of the system, they significantly accelerate the transition toward a more sustainable land allocation in the medium term

Developing and testing a new Ecological Quality Status index based on marine nematode metabarcoding: A proof of concept

Nematodes are the most diverse and dominant group of marine meiofauna with high potential as bioindicators of the ecological quality status (EcoQS). The present study explores, for the first time, the applicability of the nematode metabarcoding to infer EcoQS index based on the calibration of ecological behaviors of nematodes Amplicon Sequence Variants (ASVs). To achieve this, we analyzed the nematode community in sediment eDNA samples collected in 2018 and 2021 in areas around three offshore oil platforms in the Danish west coast of the North Sea. One training dataset based on eDNA and environmental data from the three platforms in 2021 covering a wide range of environmental gradients has been used as a training dataset to assign the nematodes ASVs to Ecological Groups. These assignments then allowed us to infer the EcoQS both around these three platforms and in an independent dataset (one of the platforms sampled in 2018). The EcoQS inferred from the nema-gAMBI is perfectly in line with the pollution gradient of the platforms. In fact, stations located close to the platforms (i.e., 100 m and 250 m) show a relatively lower EcoQS than those at greater distance (i.e., reference or 3000 m). The nema-gAMBI seems to capture well the EcoQS variability around platforms and correlates well with the environmental parameters (e.g., trace element and hydrocarbon pollution). Indeed, the nema-gAMBI is positively and significantly correlated with the traditional macrofauna-based AMBI. The present proof of concept strongly advocates for the application of the nematode eDNA-based index in the evaluation of EcoQS