Comparison of Serum Lipoproteins in non-pregnant women of reproductive age group with normal pregnant women without PIH and pregnant women with PIH

Abstract

Aim: To evaluate the levels of Serum Lipoproteins in Pregnancy Induced Hypertension. Material and Methods: A cross sectional study was conducted in Department of Biochemistry, Patna. Medical College and Hospital, Patna, Bihar, India from July 2019 to January 2020. Total 300 patients include 100 non-pregnant,100 pregnant and 100 PIH cases. Serum cholesterol, lipoproteins and triglyceride levels were evaluated for each of the three groups. Results: In the present study there was no significant difference in serum cholesterol levels between group I (normal, non-pregnant women) and group II (normal pregnant women). However, a significant difference was observed between group I and group III (pregnancy with PIH) the P values being<0.001. The serum cholesterol levels in group III were significantly higher than those in group I. However, there was a significant difference in serum cholesterol levels between group II and group III. The P value being <0.001. Conclusion: Pregnancy induced hypertension is a frequent complication during pregnancy which if advanced may be fatal for both mother and foetus. Endothelial damage might involve elevated serum triglycerides which may have a value that can be used as screening markers in early stages of pregnancy leading to preeclampsia in future. Keywords: Lipid profile, PIH, pregnanc

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